Journal article
Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes: A Randomized Clinical Trial
Abstract
Importance: Type 1 diabetes requires major lifestyle changes and carries increased morbidity and mortality. Prevention or delay of diabetes would have major clinical effect.
Objective: To determine whether oral insulin delays onset of type 1 diabetes in autoantibody-positive relatives of patients with type 1 diabetes.
Authors
Krischer JP; Schatz DA; Bundy B; Skyler JS; Greenbaum CJ
Journal
JAMA, Vol. 318, No. 19, pp. 1891–1902
Publisher
American Medical Association (AMA)
Publication Date
November 21, 2017
DOI
10.1001/jama.2017.17070
ISSN
0098-7484