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Quantifying brain iron deposition in patients with...
Journal article

Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2*

Abstract

PURPOSE: To evaluate the sensitivity and specificity of quantitative magnetic resonance (MR) iron mapping including R2, R2* and magnetic susceptibility to differentiate patients with Parkinson's disease (PD) from healthy controls. MATERIALS AND METHODS: Thirty (30) healthy controls (HC) (64±7years old) and 20 patients with idiopathic PD (66±8years old) were studied using a 3T MR imaging scanner. R2 maps were generated from GRASE sequence while …

Authors

Barbosa JHO; Santos AC; Tumas V; Liu M; Zheng W; Haacke EM; Salmon CEG

Journal

Magnetic Resonance Imaging, Vol. 33, No. 5, pp. 559–565

Publisher

Elsevier

Publication Date

June 2015

DOI

10.1016/j.mri.2015.02.021

ISSN

0730-725X