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The influence of protein adsorption and surface...
Journal article

The influence of protein adsorption and surface modifying macromolecules on the hydrolytic degradation of a poly(ether–urethane) by cholesterol esterase

Abstract

Previous investigations have demonstrated that the inflammatory cell derived enzyme, cholesterol esterase (CE) could degrade polyurethanes (PUs) by hydrolyzing ester and urethane bonds. Studies that have investigated the development of protective coatings for PUs have reported that the polymer degradation of polyester-urethanes (PESUs) can be reduced with the use of fluorine containing surface modifying macromolecules (SMMs). Since these latter …

Authors

Jahangir R; McCloskey CB; Mc Clung WG; Labow RS; Brash JL; Santerre JP

Journal

Biomaterials, Vol. 24, No. 1, pp. 121–130

Publisher

Elsevier

Publication Date

January 2003

DOI

10.1016/s0142-9612(02)00269-7

ISSN

0142-9612