Journal article
Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials
Abstract
BACKGROUND: There have been 13 randomised controlled trials of prophylactic amiodarone in patients with recent myocardial infarction (MI) or congestive heart failure (CHF). None of these was powered to detect a mortality reduction of about 20%. We undertook a meta-analysis, based on data from individual patients, to provide a more sensitive and accurate assessment of the benefits and risks of prophylactic amiodarone.
METHODS: Individual data …
Authors
Investigators ATM-A
Journal
The Lancet, Vol. 350, No. 9089, pp. 1417–1424
Publisher
Elsevier
Publication Date
November 1997
DOI
10.1016/s0140-6736(97)05281-1
ISSN
0140-6736