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Effect of Hypoglycemia on Brain Structure in...
Journal article

Effect of Hypoglycemia on Brain Structure in People With Type 2 Diabetes: Epidemiological Analysis of the ACCORD-MIND MRI Trial

Abstract

OBJECTIVE: The effect of hypoglycemia related to treatment of type 2 diabetes mellitus (T2DM) on brain structure remains unclear. We aimed to assess whether symptomatic severe hypoglycemia is associated with brain atrophy and/or white matter abnormalities. RESEARCH DESIGN AND METHODS: We included T2DM participants with brain MRI from the Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) trial. Symptomatic severe …

Authors

Zhang Z; Lovato J; Battapady H; Davatzikos C; Gerstein HC; Ismail-Beigi F; Launer LJ; Murray A; Punthakee Z; Tirado AA

Journal

Diabetes Care, Vol. 37, No. 12, pp. 3279–3285

Publisher

American Diabetes Association

Publication Date

December 1, 2014

DOI

10.2337/dc14-0973

ISSN

0149-5992