subject area of
- A Tool Set to Map Allosteric Networks through the NMR Chemical Shift Covariance Analysis Journal Articles
- Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding Journal Articles
- Allosteric Modulation of the Dopamine D2 Receptor by Pro-Leu-Gly-NH2 Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation Journal Articles
- Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH2 Journal Articles
- Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax Journal Articles
- Allosteric linkers in cAMP signalling Journal Articles
- Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain. Journal Articles
- Allosteric pluripotency as revealed by protein kinase A Journal Articles
- Allosteric pluripotency: challenges and opportunities Journal Articles
- Allostery Trumps Antibiotic Resistance Journal Articles
- Amyloid-Driven Allostery. Journal Articles
- An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase Journal Articles
- Catalysis and Rational Engineering of trans‐Acting pH6DZ1, an RNA‐Cleaving and Fluorescence‐Signaling Deoxyribozyme with a Four‐Way Junction Structure Journal Articles
- Colorimetric Sensing by Using Allosteric‐DNAzyme‐Coupled Rolling Circle Amplification and a Peptide Nucleic Acid–Organic Dye Probe Journal Articles
- Cooperativity of papain-substrate interaction energies in the S2 to S2' subsites Journal Articles
- Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function Journal Articles
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Design and Synthesis of Photoaffinity-Labeling Ligands of the
l -Prolyl-l -leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor Journal Articles - Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G Journal Articles
- Dynamical Basis of Allosteric Activation for the Plasmodium falciparum Protein Kinase G Journal Articles
- Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains Journal Articles
- Effects of the Dopamine D2 Allosteric Modulator, PAOPA, on the Expression of GRK2, Arrestin-3, ERK1/2, and on Receptor Internalization Journal Articles
- Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662 Journal Articles
- Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP Journal Articles
- Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin Journal Articles
- Evolution of Allosteric Control in Glycogen Phosphorylase Journal Articles
- Identification of New Batrachotoxin-sensing Residues in Segment IIIS6 of the Sodium Channel Journal Articles
- Identification of core allosteric sites through temperature- and nucleus-invariant chemical shift covariance Journal Articles
- Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Journal Articles
- Intertissue regulation of carnitine palmitoyltransferase I (CPTI): Mitochondrial membrane properties and gene expression in rainbow trout (Oncorhynchus mykiss) Journal Articles
- Label-Free Assay for Thermodynamic Analysis of Protein−Ligand Interactions: A Multivariate Strategy for Allosteric Ligand Screening Journal Articles
- Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function Journal Articles
- Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms Journal Articles
- Mapping Allostery through Equilibrium Perturbation NMR Spectroscopy Journal Articles
- Mapping allostery through the covariance analysis of NMR chemical shifts Journal Articles
- Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR Journal Articles
- Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist Journal Articles
- Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase Conferences
- Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site Journal Articles
- Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases Journal Articles
- Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations Journal Articles
- PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia Journal Articles
- Partial purification and characterization of the ribonucleotide reductase induced by herpes simplex virus infection of mammalian cells Journal Articles
- Signaling through dynamic linkers as revealed by PKA Journal Articles
- Simple Fluorescent Sensors Engineered with Catalytic DNA ‘MgZ’ Based on a Non-Classic Allosteric Design Journal Articles
- Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy Journal Articles
- Specific binding of photoaffinity-labeling peptidomimetics of Pro-Leu-Gly-NH2 to the dopamine D2L receptor: Evidence for the allosteric modulation of the dopamine receptor Journal Articles
- Stimulation of nicotinic acetylcholine receptors protects motor neurons Journal Articles
- Structure and function of aspartate transcarbamoylase studied using chymotrypsin as a probe Journal Articles
- Subunit interactions in aspartate transcarbamylase. A model for the allosteric mechanism Journal Articles
- Subunit interactions in aspartate transcarbamylase. Characterization of a complex between the catalytic and the regulatory subunits Journal Articles
- Subunit interactions in aspartate transcarbamylase. The interaction between catalytic and regulatory subunits and the effect of ligands Journal Articles
- The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR Journal Articles
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The structure of the apo
cAMP ‐binding domain ofHCN 4 – a stepping stone toward understanding thecAMP ‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels Journal Articles - Transformation of Pro-Leu-Gly-NH2 Peptidomimetic Positive Allosteric Modulators of the Dopamine D2 Receptor into Negative Modulators Journal Articles
- Understanding cAMP-Dependent Allostery by NMR Spectroscopy: Comparative Analysis of the EPAC1 cAMP-Binding Domain in Its Apo and cAMP-Bound States Journal Articles
- Use of Allosteric Targets in the Discovery of Safer Drugs Journal Articles
- cAMP-dependent allostery and dynamics in Epac: an NMR view Journal Articles