subject area of
- A Tool Set to Map Allosteric Networks through the NMR Chemical Shift Covariance Analysis Academic Article
- Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding Academic Article
- Allosteric Modulation of the Dopamine D2 Receptor by Pro-Leu-Gly-NH2 Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation Academic Article
- Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH2 Academic Article
- Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax Academic Article
- Allosteric linkers in cAMP signalling Academic Article
- Allosteric pluripotency as revealed by protein kinase A Academic Article
- Allosteric pluripotency: challenges and opportunities Academic Article
- Allostery Trumps Antibiotic Resistance Academic Article
- An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase Academic Article
- Catalysis and Rational Engineering of trans-Acting pH6DZ1, an RNA-Cleaving and Fluorescence-Signaling Deoxyribozyme with a Four-Way Junction Structure Academic Article
- Colorimetric Sensing by Using Allosteric-DNAzyme-Coupled Rolling Circle Amplification and a Peptide Nucleic Acid-Organic Dye Probe Academic Article
- Cooperativity of papain-substrate interaction energies in the S2 to S2' subsites Academic Article
- Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function Academic Article
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Design and Synthesis of Photoaffinity-Labeling Ligands of the
l -Prolyl-l -leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor Academic Article - Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G Academic Article
- Dynamical Basis of Allosteric Activation for the Plasmodium falciparum Protein Kinase G Academic Article
- Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains Academic Article
- Effects of the Dopamine D2 Allosteric Modulator, PAOPA, on the Expression of GRK2, Arrestin-3, ERK1/2, and on Receptor Internalization Academic Article
- Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662 Academic Article
- Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP Academic Article
- Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin Academic Article
- Evolution of Allosteric Control in Glycogen Phosphorylase Academic Article
- Identification of New Batrachotoxin-sensing Residues in Segment IIIS6 of the Sodium Channel Academic Article
- Identification of core allosteric sites through temperature- and nucleus-invariant chemical shift covariance Academic Article
- Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Academic Article
- Intertissue regulation of carnitine palmitoyltransferase I (CPTI): Mitochondrial membrane properties and gene expression in rainbow trout (Oncorhynchus mykiss) Academic Article
- Label-Free Assay for Thermodynamic Analysis of Protein−Ligand Interactions: A Multivariate Strategy for Allosteric Ligand Screening Academic Article
- Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function Academic Article
- Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms Academic Article
- Mapping Allostery through Equilibrium Perturbation NMR Spectroscopy Academic Article
- Mapping allostery through the covariance analysis of NMR chemical shifts Academic Article
- Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR Academic Article
- Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist Academic Article
- Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase Conference Paper
- Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site Academic Article
- Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases Academic Article
- Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations Academic Article
- PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia Academic Article
- Partial purification and characterization of the ribonucleotide reductase induced by herpes simplex virus infection of mammalian cells Academic Article
- Signaling through dynamic linkers as revealed by PKA Academic Article
- Simple Fluorescent Sensors Engineered with Catalytic DNA ‘MgZ’ Based on a Non-Classic Allosteric Design Academic Article
- Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy Academic Article
- Specific binding of photoaffinity-labeling peptidomimetics of Pro-Leu-Gly-NH2 to the dopamine D2L receptor: Evidence for the allosteric modulation of the dopamine receptor Academic Article
- Stimulation of nicotinic acetylcholine receptors protects motor neurons Academic Article
- Structure and function of aspartate transcarbamoylase studied using chymotrypsin as a probe Academic Article
- Subunit interactions in aspartate transcarbamylase. A model for the allosteric mechanism Academic Article
- Subunit interactions in aspartate transcarbamylase. Characterization of a complex between the catalytic and the regulatory subunits Academic Article
- Subunit interactions in aspartate transcarbamylase. The interaction between catalytic and regulatory subunits and the effect of ligands Academic Article
- The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR Academic Article
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The structure of the apo
cAMP ‐binding domain ofHCN 4 – a stepping stone toward understanding thecAMP ‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels Academic Article - Transformation of Pro-Leu-Gly-NH2 Peptidomimetic Positive Allosteric Modulators of the Dopamine D2 Receptor into Negative Modulators Academic Article
- Understanding cAMP-Dependent Allostery by NMR Spectroscopy: Comparative Analysis of the EPAC1 cAMP-Binding Domain in Its Apo and cAMP-Bound States Academic Article
- Use of Allosteric Targets in the Discovery of Safer Drugs Academic Article
- cAMP-dependent allostery and dynamics in Epac: an NMR view Academic Article