Journal article
β‐thalassemia intermedia caused by compound heterozygosity for Hb Malay (β codon 19 AAC→AGC; Asn→Ser) and codons 41/42 (‐CTTT) β0‐thalassemia mutation
Abstract
We report a case of beta-thalassemia intermedia caused by compound heterozygosity for hemoglobin (Hb) Malay and codon 41/42 (-CTTT) beta(0)-thalassemia mutation in a 38-year-old Chinese woman. This patient has long-standing anemia with a baseline Hb level of around 70 g/L. She worked as a full-time cashier and had not required regular blood transfusions. Nevertheless, she had splenomegaly necessitating splenectomy, cholelithiasis, and iron …
Authors
Ma SK; Chow EYD; Chan AYY; Kung NNS; Waye JS; Chan LC; Chui DHK
Journal
American Journal of Hematology, Vol. 64, No. 3, pp. 206–209
Publisher
Wiley
Publication Date
7 2000
DOI
10.1002/1096-8652(200007)64:3<206::aid-ajh12>3.0.co;2-#
ISSN
0361-8609