Journal article
Effects of Cardiac Autonomic Dysfunction on Mortality Risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial
Abstract
OBJECTIVE: Intensive therapy targeting normal blood glucose increased mortality compared with standard treatment in a randomized clinical trial of 10,251 participants with type 2 diabetes at high-risk for cardiovascular disease (CVD) events. We evaluated whether the presence of cardiac autonomic neuropathy (CAN) at baseline modified the effect of intensive compared with standard glycemia treatment on mortality outcomes in the Action to Control …
Authors
Pop-Busui R; Evans GW; Gerstein HC; Fonseca V; Fleg JL; Hoogwerf BJ; Genuth S; Grimm RH; Corson MA; Prineas R
Journal
Diabetes Care, Vol. 33, No. 7, pp. 1578–1584
Publisher
American Diabetes Association
Publication Date
July 1, 2010
DOI
10.2337/dc10-0125
ISSN
0149-5992