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Effects of intensive glucose lowering on brain...
Journal article

Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy

Abstract

BACKGROUND: People with type 2 diabetes are at risk of cognitive impairment and brain atrophy. We aimed to compare the effects on cognitive function and brain volume of intensive versus standard glycaemic control. METHODS: The Memory in Diabetes (MIND) study was done in 52 clinical sites in North America as part of Action to Control Cardiovascular Risk in Diabetes (ACCORD), a double two-by-two factorial parallel group randomised trial. …

Authors

Launer LJ; Miller ME; Williamson JD; Lazar RM; Gerstein HC; Murray AM; Sullivan M; Horowitz KR; Ding J; Marcovina S

Journal

The Lancet Neurology, Vol. 10, No. 11, pp. 969–977

Publisher

Elsevier

Publication Date

11 2011

DOI

10.1016/s1474-4422(11)70188-0

ISSN

1474-4422