Journal article
Dronedarone in High-Risk Permanent Atrial Fibrillation
Abstract
BACKGROUND: Dronedarone restores sinus rhythm and reduces hospitalization or death in intermittent atrial fibrillation. It also lowers heart rate and blood pressure and has antiadrenergic and potential ventricular antiarrhythmic effects. We hypothesized that dronedarone would reduce major vascular events in high-risk permanent atrial fibrillation.
METHODS: We assigned patients who were at least 65 years of age with at least a 6-month history of …
Authors
Connolly SJ; Camm AJ; Halperin JL; Joyner C; Alings M; Amerena J; Atar D; Avezum Á; Blomström P; Borggrefe M
Journal
New England Journal of Medicine, Vol. 365, No. 24, pp. 2268–2276
Publisher
Massachusetts Medical Society
Publication Date
December 15, 2011
DOI
10.1056/nejmoa1109867
ISSN
0028-4793