ATP-Dependent Silver Transport across the Basolateral Membrane of Rainbow Trout Gills

Silver has been shown to be extremely toxic to freshwater teleosts, acting to inhibit Na(+) uptake at the gills, due to the inactivation of branchial Na(+)/K(+)-ATPase activity. However, the gills are also a route by which silver may enter the fish. Therefore, this study focuses on the mechanism of transport of this nonessential metal across the basolateral membrane of the gill cell, using basolateral membrane vesicles (BLMV) prepared from the …