Epinephrine Facilitates Neurogenic Responses in Isolated Segments of Dog Mesenteric Arteries

Summary: Epinephrine (EPI) bitartrate (10-9-10-8 M) significantly enhanced tension development in response to electrical field stimulation in isolated segments of dog mesenteric arteries. Responses to exogenous norepinephrine (NE) were generally unaffected, indicating that the EPI-induced increases in response to field stimulation are not explicable in terms of changes in postjunctional sensitivity. The facilitatory effects of EPI (5 × 10-9 M) …