Journal article
Epidermal growth factor and transforming growth factor-β differently modulate the acute phase response elicited by interleukin-6 in cultured liver cells from man, rat and mouse
Abstract
1. Complex effects of principal inflammatory cytokines (IL-6, IL-1, TNF, IFN-gamma) on acute phase protein synthesis and other metabolic processes in cultured liver cells are briefly reviewed. 2. Molecular properties and biological functions of transforming growth factor-beta and epidermal growth factor are compared. 3. The effects of these factors with respect to both amino acid uptake and acute phase protein synthesis are described in detail. …
Authors
Rokita H; Bereta J; Koj A; Gordon AH; Gauldie J
Journal
Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, Vol. 95, No. 1, pp. 41–45
Publisher
Elsevier
Publication Date
1 1990
DOI
10.1016/0300-9629(90)90007-f
ISSN
1095-6433