Journal article
Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome
Abstract
Inappropriate release of proteases from inflammatory and stromal cells can lead to destruction of the lung parenchyma. Antiproteinases such as alpha-1-proteinase inhibitor (alpha1-Pi), secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (elafin) control excess production of human neutrophil elastase. In the present study, the concentrations of alpha1-Pi, SLPI and elafin found in bronchoalveolar lavage (BAL) fluid …
Authors
Sallenave JM; Donnelly SC; Grant IS; Robertson C; Gauldie J; Haslett C
Journal
European Respiratory Journal, Vol. 13, No. 5, pp. 1029–1036
Publisher
European Respiratory Society (ERS)
Publication Date
May 1, 1999
DOI
10.1183/09031936.99.13510299
ISSN
0903-1936