Journal article
Preoperative Enoxaparin Versus Postoperative Semuloparin Thromboprophylaxis in Major Abdominal Surgery
Abstract
OBJECTIVE: To compare efficacy and safety of thromboprophylaxis with semuloparin started postoperatively versus enoxaparin started preoperatively in major abdominal surgery.
BACKGROUND: Venous thromboembolism is an important complication following major abdominal surgery. Semuloparin is a novel ultra-low-molecular-weight heparin with high antifactor Xa and minimal antifactor IIa activity.
Authors
Kakkar AK; Agnelli G; Fisher W; George D; Lassen MR; Mismetti P; Mouret P; Murphy J; Lawson F; Turpie AGG
Journal
Annals of Surgery, Vol. 259, No. 6, pp. 1073–1079
Publisher
Wolters Kluwer
Publication Date
June 2014
DOI
10.1097/sla.0000000000000430
ISSN
0003-4932
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AbdomenAdolescentAdultAgedAged, 80 and overDose-Response Relationship, DrugDouble-Blind MethodEnoxaparinFemaleFibrinolytic AgentsFollow-Up StudiesHeparin, Low-Molecular-WeightHumansMaleMiddle AgedPostoperative ComplicationsPostoperative PeriodPreoperative PeriodRetrospective StudiesSurgical Procedures, OperativeTreatment OutcomeVenous ThromboembolismYoung Adult