Journal article
Turnover and fate of fibrinogen and platelets at the rabbit aorta wall immediately after a balloon de-endothelializing injury in vivo
Abstract
A de-endothelializing injury to the artery wall in vivo results in a rapid procoagulant response at the surface of the exposed subendothelium. Activated tissue factor (TF)-bearing cells and hemostasis factors located at the site of injury respond by producing thrombin, and within minutes the principal thrombus-forming, blood-borne components (platelets, fibrinogen) accumulate at the site. To compare their behaviors, the rates of uptake and …
Authors
Hatton MWC; Ross B; Timleck M; Southward SMR; Richardson M
Journal
Thrombosis and Haemostasis, Vol. 96, No. 01, pp. 60–67
Publisher
Thieme
Publication Date
2006
DOI
10.1160/th05-11-0759
ISSN
0340-6245