Journal article
Pressurized Aerosol versus Jet Aerosol Delivery to Mechanically Ventilated Patients Comparison of Dose to the Lungs
Abstract
The purpose of this study was to compare deposition of aerosol to the lung from a metered-dose inhaler (MDI) and aerosol holding chamber and from a jet nebulizer in ventilator-dependent patients. Twenty-one patients were entered into the study, all receiving assisted ventilation and inhaled bronchodilators because of airflow limitation. The average age was 68 yr; there were 10 men and 11 women. The patients were randomized to receive either 4 …
Authors
Fuller HD; Dolovich MB; Posmituck G; Pack WW; Newhouse MT
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 141, No. 2, pp. 440–444
Publisher
American Thoracic Society
Publication Date
February 1990
DOI
10.1164/ajrccm/141.2.440
ISSN
1073-449X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AerosolsAgedDose-Response Relationship, DrugEquipment DesignFemaleFenoterolHumansIntermittent Positive-Pressure VentilationLungMaleNebulizers and VaporizersPositive-Pressure RespirationRadionuclide ImagingRandomized Controlled Trials as TopicSodium Pertechnetate Tc 99mTechnetium Tc 99m Sulfur Colloid