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Incorporating multiple interventions in...
Journal article

Incorporating multiple interventions in meta-analysis: an evaluation of the mixed treatment comparison with the adjusted indirect comparison

Abstract

BackgroundComparing the effectiveness of interventions is now a requirement for regulatory approval in several countries. It also aids in clinical and public health decision-making. However, in the absence of head-to-head randomized trials (RCTs), determining the relative effectiveness of interventions is challenging. Several methodological options are now available. We aimed to determine the comparative validity of the adjusted indirect …

Authors

O'Regan C; Ghement I; Eyawo O; Guyatt GH; Mills EJ

Journal

Trials, Vol. 10, No. 1,

Publisher

Springer Nature

Publication Date

12 2009

DOI

10.1186/1745-6215-10-86

ISSN

1468-6708