Conference
SOX2 IDENTIFIES THE TREATMENT-REFRACTORY STEM CELL POPULATION IN GROUP 2 MEDULLOBLASTOMA
Abstract
BACKGROUND: Brain tumors represent the leading cause of childhood cancer mortality, of which medulloblastoma (MB) is the most frequent malignant pediatric brain tumor. Recent studies have demonstrated the presence of several MB molecular subgroups, each distinct in terms of prognosis and predicted therapeutic response. Although, group 2 MBs characterized by activation of the sonic hedgehog (Shh) signaling pathway have been of particular …
Authors
Singh SK; Manoranjan B; Venugopal C; Vora P; McFarlane N; Garg N; Singh M; Mann A; Bakhshinyan D; Mahendran S
Volume
16
Pagination
pp. iii5-iii5
Publisher
Oxford University Press (OUP)
Publication Date
July 1, 2014
DOI
10.1093/neuonc/nou206.16
Conference proceedings
Neuro-Oncology
Issue
suppl_3
ISSN
1522-8517