Journal article
A proton magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in acute mania
Abstract
BACKGROUND: Several neurochemical abnormalities have been reported in bipolar disorder (BD), but the exact mechanisms that underlie its pathophysiology remain to be elucidated. Proton magnetic resonance spectroscopy (1HMRS) allows in vivo measurements of certain neurometabolites in the human brain. 1HMRS was used to investigate the dorsolateral prefrontal cortex (DLPFC) in bipolar subjects during a manic or mixed phase. N-acetyl-L-aspartate …
Authors
Frey BN; Folgierini M; Nicoletti M; Machado‐Vieira R; Stanley JA; Soares JC; Kapczinski F
Journal
Human Psychopharmacology Clinical and Experimental, Vol. 20, No. 2, pp. 133–139
Publisher
Wiley
Publication Date
March 2005
DOI
10.1002/hup.671
ISSN
0885-6222