Conference
Properties of the Stromal Cell in Giant Cell Tumor of Bone
Abstract
The histiogenesis and mechanisms of bone destruction in giant cell tumor (GCT) of bone are not well understood. We asked whether the spindle-like stromal cells of GCT of bone exhibit osteoblastic properties, and whether the stromal cells produce active matrix-degrading proteases in vitro. We performed immunohistochemistry on 17 paraffin-embedded archival specimens with a pathologic diagnosis of GCT with monoclonal antibodies for the …
Authors
Ghert M; Simunovic N; Cowan RW; Colterjohn N; Singh G
Volume
459
Pagination
pp. 8-13
Publisher
Wolters Kluwer
Publication Date
June 2007
DOI
10.1097/blo.0b013e31804856a1
Conference proceedings
Clinical Orthopaedics and Related Research®
Issue
&NA;
ISSN
0009-921X