Journal article
Is Isolated Palatal Anomaly an Indication to Screen for 22q11 Region Deletion?
Abstract
OBJECTIVE: Velocardiofacial syndrome (VCFS) is the most common multiple anomaly disorder associated with palatal clefting. Cytogenetic hemizygous deletion of 22q11 region is found in 80% of patients. The frequency of 22q11 deletion in patients presenting with isolated palatal anomalies has not been fully assessed. Our objective was to determine the frequency of the deletion in patients with isolated palatal anomalies.
DESIGN: Patients were …
Authors
Reish O; Finkelstein Y; Mesterman R; Nachmani A; Wolach B; Fejgin M; Amiel A
Journal
The Cleft Palate-Craniofacial Journal, Vol. 40, No. 2, pp. 176–179
Publisher
SAGE Publications
Publication Date
March 2003
DOI
10.1597/1545-1569_2003_040_0176_iipaai_2.0.co_2
ISSN
1055-6656