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Generation of in vitro B-CLL specific HLA class I...
Journal article

Generation of in vitro B-CLL specific HLA class I restricted CTL responses using autologous dendritic cells pulsed with necrotictumor lysate

Abstract

New approaches in the treatment of chronic B lymphocytic leukemia (B-CLL) have led to improved clinical response rates. In this setting there is a need to evaluate novel therapeutic approaches that aim to eradicate minimal residual B-CLL cells following an initial favorable response. The use of tumor lysate-pulsed dendritic cells (DC) represents a potentially important development in the field of cancer vaccination. B-CLL is ideally suited for …

Authors

Suresh K; Fraser G; Scheid E; Leber B; Gauldie J; Foley R

Journal

Leukemia & Lymphoma, Vol. 47, No. 2, pp. 297–306

Publisher

Taylor & Francis

Publication Date

January 2006

DOI

10.1080/10428190500301231

ISSN

1042-8194