Journal article
Larazotide Acetate for Persistent Symptoms of Celiac Disease Despite a Gluten-Free Diet: A Randomized Controlled Trial
Abstract
BACKGROUND & AIMS: Celiac disease (CeD) is a prevalent autoimmune condition. Recurrent signs and symptoms are common despite treatment with a gluten-free diet (GFD), yet no approved or proven nondietary treatment is available.
METHODS: In this multicenter, randomized, double-blind, placebo-controlled study, we assessed larazotide acetate 0.5, 1, or 2 mg 3 times daily to relieve ongoing symptoms in 342 adults with CeD who had been on a GFD for …
Authors
Leffler DA; Kelly CP; Green PHR; Fedorak RN; DiMarino A; Perrow W; Rasmussen H; Wang C; Bercik P; Bachir NM
Journal
Gastroenterology, Vol. 148, No. 7, pp. 1311–1319.e6
Publisher
Elsevier
Publication Date
June 2015
DOI
10.1053/j.gastro.2015.02.008
ISSN
0016-5085