Social Variables Predict Gains in Cognitive Scores across the Preschool Years in Children with Birth Weights 500 to 1250 Grams Academic Article uri icon

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abstract

  • OBJECTIVE: To determine the extent that social variables influence cognitive development of very low birth weight (VLBW) infants across the preschool years. STUDY DESIGN: Participants were VLBW (500-1250 g) children enrolled in the Caffeine for Apnea of Prematurity randomized trial between 1999 and 2004. We investigated the relationships between 4 potential social advantages: higher maternal education, higher paternal education, caregiver employment, and 2 biologic parents in the same home--and gain in cognitive scores. Cognitive assessments were performed at the corrected ages of 18 months (Mental Development Index score on the Bayley Scales of Infant Development II) and 5 years (Full Scale IQ on the Wechsler Preschool and Primary Scale of Intelligence III). Cognitive gain was computed by subtracting each individual 18-month Mental Development Index score from the corresponding Full Scale IQ at 5 years. RESULTS: Data were available for 1347 children. Mean (SD) cognitive scores were 90.8 (15.7) at 18 months and 98.9 (14.5) at 5 years. Multivariable regression showed that higher maternal education, higher paternal education, and caregiver employment had independent and additive effects of similar size on cognitive gain (P < .001); the mean cognitive gain between 18 months and 5 years increased by 3.6 points in the presence of each of these advantages. When all 3 were present, cognitive scores improved on average by 10.9 points compared with children without any of these advantages. CONCLUSION: In VLBW children, a count of 3 social advantages strongly predicts gains in cognitive scores across the preschool years.

authors

  • Manley, Brett J
  • Roberts, Robin S
  • Doyle, Lex W
  • Schmidt, Barbara
  • Anderson, Peter J
  • Barrington, Keith J
  • Böhm, Birgitta
  • Golan, Agneta
  • van Wassenaer-Leemhuis, Aleid G
  • Davis, Peter G
  • Schmidt, Barbara
  • D'Ilario, Judy
  • Cairnie, Janice
  • Dix, Joanne
  • Anne Adams, Beth
  • Warriner, Erin
  • Kim, Marie
  • Anderson, Peter
  • Davis, Peter
  • Doyle, Lex
  • Argus, Brenda
  • Callanan, Catherine
  • Davis, Noni
  • Duff, Julianne
  • McDonald, Marion
  • Asztalos, Elizabeth
  • Hohn, Denise
  • Lacy, Maralyn
  • Haslam, Ross
  • Barnett, Christopher
  • Goodchild, Louise
  • Lontis, Rosslyn Marie
  • Fraser, Simon
  • Keng, Julie
  • Saunders, Kerryn
  • Opie, Gillian
  • Kelly, Elaine
  • Woods, Heather
  • Marchant, Emma
  • Turner, Anne-Marie
  • Davis, Noni
  • Magrath, Emma
  • Williamson, Amanda
  • Bairam, Aida
  • Bélanger, Sylvie
  • Fraser, Annie
  • Blayney, Marc
  • Lemyre, Brigitte
  • Frank, Jane
  • Solimano, Alfonso
  • Synnes, Anne
  • Grunau, Ruth E
  • Hubber-Richard, Philippa
  • Rogers, Marilyn
  • Mackay, Margot
  • Petrie-Thomas, Julianne
  • Butt, Arsalan
  • van Wassenaer, Aleid
  • Nuytemans, Debbie
  • Houtzager, Bregje
  • van Sonderen, Loekie
  • Regev, Rivka
  • Itzchack, Netter
  • Arnon, Shmuel
  • Chalaf, Adiba
  • Ohlsson, Arne
  • O'Brien, Karel
  • Hamilton, Anne-Marie
  • Chan, May Lee
  • Sankaran, Koravangattu
  • Proctor, Pat
  • Golan, Agneta
  • Goldsch-Lerman, Esther
  • Reynolds, Graham
  • Dromgool, Barbara
  • Meskell, Sandra
  • Parr, Vanessa
  • Maher, Catherine
  • Broom, Margaret
  • Kecskes, Zsuzsoka
  • Ringland, Cathy
  • McMillan, Douglas
  • Spellen, Elizabeth
  • Sauve, Reginald S
  • Christianson, Heather
  • Anseeuw-Deeks, Deborah
  • Creighton, Dianne
  • Heath, Jennifer
  • Alvaro, Ruben
  • Chiu, Aaron
  • Porter, Ceceile
  • Turner, Gloria
  • Moddemann, Diane
  • Granke, Naomi
  • Penner, Karen
  • Bow, Jane
  • Mulder, Antonius
  • Wassenberg, Renske
  • van der Hoeven, Markus
  • Clarke, Maxine
  • Parfitt, Judy
  • Parker, Kevin
  • Nwaesei, Chukwuma
  • Ryan, Heather
  • Saunders, Cory
  • Schulze, Andreas
  • Wermuth, Inga
  • Hilgendorff, Anne
  • Flemmer, Andreas W
  • Herlenius, Eric
  • Legnevall, Lena
  • Lagercrantz, Hugo
  • Matthew, Derek
  • Amos, Wendy
  • Tulsiani, Suresh
  • Tan-Dy, Cherrie
  • Turner, Marilyn
  • Phelan, Constance
  • Shinwell, Eric S
  • Levine, Michael
  • Juster-Reicher, Ada
  • Khairy, May
  • Grier, Patricia
  • Vachon, Julie
  • Perepolkin, Larissa
  • Barrington, Keith J
  • Sinha, Sunil Kumar
  • Tin, Win
  • Fritz, Susan
  • Walti, Herve
  • Royer, Diane
  • Halliday, Henry
  • Millar, David
  • Mayes, Clifford
  • McCusker, Christopher
  • McLaughlin, Olivia
  • Fahnenstich, Hubert
  • Tillmann, Bettina
  • Weber, Peter
  • Wariyar, Unni
  • Embleton, Nicholas
  • Swamy, Ravi
  • Bucher, Hans U
  • Fauchere, Jean-Claude
  • Dietz, Vera
  • Harikumar, Chidambara
  • Tin, Win
  • Fritz, Susan
  • Schmidt, Barbara
  • Anderson, Peter J
  • Asztalos, Elizabeth V
  • Barrington, Keith J
  • Davis, Peter G
  • Dewey, Deborah
  • Doyle, Lex W
  • Grunau, Ruth E
  • Moddemann, Diane
  • Ohlsson, Arne
  • Roberts, Robin S
  • Solimano, Alfonso
  • Tin, Win
  • Gent, Michael
  • Fraser, William
  • Hey, Edmund
  • Perlman, Max
  • Thorpe, Kevin
  • Gray, Shari
  • Roberts, Robin Sydney
  • Chambers, Carole
  • Costantini, Lorrie
  • Yacura, Wendy
  • McGean, Erin
  • Scapinello, Lori

publication date

  • April 2015