selected scholarly activity
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chapters
- N ‐of‐1 Randomized Clinical Trials in Pharmacoepidemiology. 665-680. 2006
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conferences
- Outcome of patients treated with plasma or prothrombin complex concentrates for warfarin related intracerebral hemorrhage. Journal of Thrombosis and Haemostasis. 555-555. 2013
- Neurologic Safety Event Rates in the SENTIS Control Population. Stroke. E258-E258. 2011
- PIH11 ECONOMIC EVALUATION ALONGSIDE THE CAFFEINE FOR APNEA OF PREMATURITY (CAP) TRIAL: SHORT TERM OUTCOMES. Value in Health. A164-A164. 2009
- Why Cancer Patients Enter Randomized Clinical Trials: Exploring the Factors That Influence Their Decision. Journal of Clinical Oncology. 4312-4318. 2004
- 270 A Randomized Controlled Trial of Low vs High Hemoglobin Thresholds for Transfusion in Extremely Low-Birth-Weight Infants. Pediatric Research. 510-510. 2004
- Prevention and 18-month outcome of serious pulmonary hemorrhage in extremely-low-birth-weight (ELBW) infants: Results from the trial of indomethacin prophylaxis in preterms (TIPP). Pediatric Research. 456A-456A. 2004
- HEat Loss Prevention (HELP) in the delivery room: A randomized clinical trial (RCT) in very preterm infants. Pediatric Research. 374A-374A. 2003
- Why does indomethacin prophylaxis prevent patent ductus arteriosus (PDA), but not bronchopulmonary dysplasia (BPD)?. Pediatric Research. 354A-354A. 2003
- Predicting long-term outcome in extremely-low-birth-weight infants: Do we really have to wait until a corrected age of 18 months?. Pediatric Research. 295A-295A. 2002
- Randomised controlled trial of low-dose erythromycin in preterm infants with feed intolerance. Pediatric Research. 379A-380A. 2002
- Retrospective economic evaluation of the controlled trial of indomethacin prophylaxis in preterms (TIPP). Pediatric Research. 379A-379A. 2002
- Symptomatic intracranial hemorrhage after intraarterial thrombolysis with recombinant prourokinase in acute ischemic stroke: The PROACT II study. Neurology. A260-A261. 2000
- Effect of pacemaker dependency on the benefit of physiologic over ventricular pacing. Circulation. 643-643. 1999
- Risk factors of hospitalization for heart failure in the Canadian Trial of Physiologic Pacing. Circulation. 465-465. 1999
- DEPRESSION IS ASSOCIATED WITH HIGHER MORTALITY IN PATIENTS WITH A HISTORY OF VENTRICULAR FIBRILLATION/TACHYCARDIA. Psychosomatic Medicine. 126-126. 1999
- The effect of ejection fraction on the relative benefit of the implantable defibrillator in the Canadian implantable defibrillator study. Circulation. 93-93. 1998
- Randomized Controlled Trial of Exercise Training in Patients With Congestive Heart Failure (EXERT). Journal of the American College of Cardiology. 508A-509A. 1998
- The Impact of Time to Thrombolytic Therapy on Outcome in Patients With Acute Myocardial Infarction (AMI). Journal of the American College of Cardiology. 453A-453A. 1998
- Right ventricular infarction: Prognostic value of radionuclide measurements.. Journal of Nuclear Medicine. 405-405. 1997
- Ticlopidine and Clopidogrel in Secondary Stroke Prevention. Cerebrovascular Diseases. 17-23. 1997
- Amiodarone side effects and laboratory abnormalities - Reliable rates from a large double-blind trial.. Circulation. 1435-1435. 1996
- LV function and infarct size predict six-month mortality post MI treated by thrombolysis. Circulation. 3829-3829. 1996
- Which patients surviving acute myocardial infarction are most likely to benefit from amiodarone?. Circulation. 1437-1437. 1996
- Which patients surviving acute myocardial infarction are most likely to benefit from amiodarone?. Circulation. 1438-1438. 1996
- A PROSPECTIVE-STUDY OF HEPARIN-INDUCED THROMBOCYTOPENIA - UNFRACTIONATED HEPARIN COMPARED WITH LOW-MOLECULAR-WEIGHT HEPARIN. Blood. A188-A188. 1994
- COMPARISON OF MORTALITY FROM ACUTE MYOCARDIAL-INFARCTION BETWEEN 1980, 1987, AND 1992 IN A GEOGRAPHICALLY-DEFINED STABLE-POPULATION. Circulation. 508-508. 1993
- HEPARIN-INDUCED THROMBOCYTOPENIA IS MORE COMMON WITH UNFRACTIONATED HEPARIN THAN WITH LOW-MOLECULAR-WEIGHT HEPARIN. Thrombosis and Haemostasis. 911-911. 1993
- EFFECT OF PREGNANCY ON AIRWAY RESPONSIVENESS AND ASTHMA SEVERITY - RELATIONSHIP TO SERUM PROGESTERONE. American Journal of Respiratory and Critical Care Medicine. S78-S78. 1991
- CANADIAN AMIODARONE MYOCARDIAL-INFARCTION ARRHYTHMIA TRIAL (CAMIAT) PILOT RESULTS. Circulation. 139-139. 1990
- Efficacy versus intent-to-treat analysis in the canadian American ticlopidine study. Contemporary Clinical Trials. 259-259. 1990
- Must the evaluator be blinded?. Contemporary Clinical Trials. 260-261. 1990
- ·58 Methodologic issues in a randomized trial to evaluate the effects of omega-3 polyunsaturated fatty acids and low-molecular-weight heparin on restenosis following percutaneous transluminal coronary angioplasty. Contemporary Clinical Trials. 276-277. 1990
- ·P-15 The operation of a central adjudication committee and its effect of the validity of the assessment of treatment benefit. Contemporary Clinical Trials. 283-283. 1990
- ·P-27 Systems of logging exclusions in multicenter clinical trials. Contemporary Clinical Trials. 288-288. 1990
- Criteria for bleeding events in a heart valve replacement trial. Contemporary Clinical Trials. 338-338. 1989
- Permanent discontinuation of study drugs in long-term clinical trials. Contemporary Clinical Trials. 338-338. 1989
- MAINTAINING BLINDNESS IN TRIALS INVOLVING ORAL ANTICOAGULANTS. Contemporary Clinical Trials. 259-259. 1988
- The use of N of 1 RCTs in drug development. Contemporary Clinical Trials. 274-275. 1988
- 94 Improvements in airway responsiveness and asthma during pregnancy: Relationship to serum progesterone. Journal of Allergy and Clinical Immunology. 192-192. 1988
- THE LIKELIHOOD RATIO LINE - A NEW METHOD FOR INTERPRETING DIAGNOSTIC-TEST RESULTS. Clinical Research. A544-A544. 1984
- MORTALITY STUDY OF CANADIAN NICKEL MINERS.. 241-260. 1983
- THE EFFECT OF ATROPINE ON ALLERGEN-INDUCED INCREASES IN BRONCHIAL RESPONSIVENESS TO HISTAMINE. American Review of Respiratory Disease. 241-241. 1983
- MORTALITY STUDIES IN ONTARIO NICKEL WORKERS - THE FALCONBRIDGE PROJECT. Annals of Clinical and Laboratory Science. 75-76. 1981
- MORTALITY STUDIES IN ONTARIO NICKEL WORKERS - THE INCO-JOHC PROJECT. Annals of Clinical and Laboratory Science. 76-76. 1981
- EFFECT OF PROVINCE OF ONTARIOS COMPULSORY SEAT-BELT LEGISLATION IN HAMILTON. American Journal of Epidemiology. 247-247. 1977
- INCREASING ABSENTEEISM AMONG WORKING MEN FOLLOWING LABELING AND TREATMENT OF THEIR HYPERTENSION. American Journal of Epidemiology. 252-252. 1977
- SHORT-TERM DISADVANTAGES OF BEING DIAGNOSED HYPERTENSIVE. Clinical Research. A266-A266. 1977
- CLINICAL DETERMINANTS OF DECISION TO TREAT PRIMARY HYPERTENSION. Clinical Research. A648-A648. 1976
- CONTROLLED CLINICAL-TRIAL OF COMPLIANCE-IMPROVING STRATEGIES IN PRIMARY HYPERTENSION. Clinical Research. A249-A249. 1976
- DETERMINANTS OF CLINICAL DECISION TO TREAT HYPERTENSION. Circulation. 129-129. 1976
- ESTIMATING SIZE OF BERKSONS BIAS. American Journal of Epidemiology. 344-344. 1976
- STUDY OF CLINICAL DECISIONS IN MANAGEMENT OF HYPERTENSION. American Journal of Epidemiology. 318-319. 1976
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journal articles
- Drugs to Prevent Bronchopulmonary Dysplasia: Effect of Baseline Risk on the Number Needed to Treat. Journal of Pediatrics. 222:244-247. 2020
- Self-reported Quality of Life at Middle School Age in Survivors of Very Preterm Birth. JAMA Pediatrics. 173:487-487. 2019
- Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness. New England Journal of Medicine. 379:1118-1127. 2018
- Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. Journal of the American Medical Association (JAMA). 319:2190-2190. 2018
- Neurobehavioral Outcomes 11 Years After Neonatal Caffeine Therapy for Apnea of Prematurity. Pediatrics. 141:e20174047. 2018
- Variation in Positive End-Expiratory Pressure Levels for Mechanically Ventilated Extremely Low Birth Weight Infants. Journal of Pediatrics. 194:28-33.e5. 2018
- Effect of Prophylactic Indomethacin in Extremely Low Birth Weight Infants Based on the Predicted Risk of Severe Intraventricular Hemorrhage. Neonatology. 113:183-186. 2018
- Oxygen Targeting in Infants Born Extremely Preterm Who Are Small for Gestational Age: A Need for Heightened Vigilance. Journal of Pediatrics. 186:9-10. 2017
- Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity. JAMA Pediatrics. 171:564-564. 2017
- Benefits of Oxygen Saturation Targeting Trials: Oximeter Calibration Software Revision and Infant Saturations. Journal of Pediatrics. 182:382-384. 2017
- Benznidazole and Posaconazole in Eliminating Parasites in Asymptomatic T. Cruzi Carriers. Journal of the American College of Cardiology. 69:939-947. 2017
- Prospective economic evaluation alongside the non-invasive ventilation trial. Journal of Perinatology. 37:61-66. 2017
- Effects of Targeting Higher or Lower Oxygen Saturations in Centers with More Versus Less Separation between Median Saturations. Journal of Pediatrics. 178:288-291.e2. 2016
- A comparison of bilevel and ventilator-delivered non-invasive respiratory support. Archives of Disease in Childhood: Fetal and Neonatal Edition. 101:21-25. 2016
- Prediction of Late Death or Disability at Age 5 Years Using a Count of 3 Neonatal Morbidities in Very Low Birth Weight Infants. Journal of Pediatrics. 167:982-986.e2. 2015
- Association Between Intermittent Hypoxemia or Bradycardia and Late Death or Disability in Extremely Preterm Infants. Journal of the American Medical Association (JAMA). 314:595-595. 2015
- Social Variables Predict Gains in Cognitive Scores across the Preschool Years in Children with Birth Weights 500 to 1250 Grams. Journal of Pediatrics. 166:870-876.e2. 2015
- Differences in Ischemic and Hemorrhagic Recurrence Rates among Race-Ethnic Groups in the PRoFESS Secondary Stroke Prevention Trial. International Journal of Stroke. 9:43-47. 2014
- Impact of Study Oximeter Masking Algorithm on Titration of Oxygen Therapy in the Canadian Oxygen Trial. Journal of Pediatrics. 165:666-671.e2. 2014
- Long-Term Effects of Caffeine Therapy for Apnea of Prematurity on Sleep at School Age. American Journal of Respiratory and Critical Care Medicine. 190:791-799. 2014
- Characteristics of Cancer Patients Presenting to an Integrative Medicine Practice-Based Research Network. Integrative Cancer Therapies. 13:405-410. 2014
- Feasibility of Comprehensive, Unattended Ambulatory Polysomnography in School-Aged Children. Journal of Clinical Sleep Medicine. 10:913-918. 2014
- Reduction in Developmental Coordination Disorder with Neonatal Caffeine Therapy. Journal of Pediatrics. 165:356-359.e2. 2014
- Trade-Off between Lower or Higher Oxygen Saturations for Extremely Preterm Infants: The First Benefits of Oxygen Saturation Targeting (BOOST) II Trial Reports Its Primary Outcome. Journal of Pediatrics. 165:6-8. 2014
- Timing of Caffeine Therapy in Very Low Birth Weight Infants. Journal of Pediatrics. 164:957-958. 2014
- Association Between Severe Retinopathy of Prematurity and Nonvisual Disabilities at Age 5 Years. Journal of the American Medical Association (JAMA). 311:523-523. 2014
- Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate. Thrombosis and Haemostasis. 112:233-239. 2014
- Only high levels of dabigatran attenuate catheter thrombosis in vitro and in rabbits. Thrombosis and Haemostasis. 112:79-86. 2014
- A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants. New England Journal of Medicine. 369:611-620. 2013
- Effects of Targeting Higher vs Lower Arterial Oxygen Saturations on Death or Disability in Extremely Preterm Infants. Journal of the American Medical Association (JAMA). 309:2111-2111. 2013
- Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo. Acta Biomaterialia. 8:4092-4100. 2012
- By Increasing the Affinity of Heparin for Fibrin, Zn2+ Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin. Biochemistry. 51:7964-7973. 2012
- Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity. Obstetrical and Gynecological Survey. 67:269-270. 2012
- Economic evaluation alongside the Premature Infants in Need of Transfusion randomised controlled trial. Archives of Disease in Childhood: Fetal and Neonatal Edition. 97:F93-F98. 2012
- Relationship Between Attrition and Neurodevelopmental Impairment Rates in Extremely Preterm Infants at 18 to 24 Months. JAMA Pediatrics. 166:178-178. 2012
- Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity. Journal of the American Medical Association (JAMA). 307:275-275. 2012
- Impact of Delivery Room Resuscitation on Outcomes up to 18 Months in Very Low Birth Weight Infants. Journal of Pediatrics. 159:546-550.e1. 2011
- Archimedes: does caffeine treatment for apnoea of prematurity improve neurodevelopmental outcome in later life?. Archives of Disease in Childhood. 96:784-784. 2011
- Effects of Prophylactic Indomethacin in Extremely Low-Birth-Weight Infants With and Without Adequate Exposure to Antenatal Corticosteroids. JAMA Pediatrics. 165:642-642. 2011
- Why would a sane clinician not prescribe prophylactic indomethacin?. Acta Paediatrica, International Journal of Paediatrics. 100:636-636. 2011
- A Clinical Prediction Model to Stratify Retinopathy of Prematurity Risk Using Postnatal Weight Gain. Pediatrics. 127:e607-e614. 2011
- Economic Evaluation of Caffeine for Apnea of Prematurity. Pediatrics. 127:e146-e155. 2011
- Mechanisms Underlying the Lack of Effect of Implantable Cardioverter-Defibrillator Therapy on Mortality in High-Risk Patients With Recent Myocardial Infarction. Circulation. 122:2645-2652. 2010
- Optimal Timing of Resumption of Warfarin After Intracranial Hemorrhage. Stroke. 41:2860-2866. 2010
- Effect of Combined Aspirin and Extended-Release Dipyridamole Versus Clopidogrel on Functional Outcome and Recurrence in Acute, Mild Ischemic Stroke. Stroke. 41:732-738. 2010
- Caffeine for Apnea of Prematurity Trial: Benefits May Vary in Subgroups. Journal of Pediatrics. 156:382-387.e3. 2010
- Prospective cohort study of three- versus two-dimensional ultrasound for prediction of oocyte maturity. Fertility and Sterility. 93:1333-1337. 2010
- HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions. Thrombosis and Haemostasis. 103:83-96. 2010
- Effect of Telmisartan on Functional Outcome, Recurrence, and Blood Pressure in Patients With Acute Mild Ischemic Stroke. Stroke. 40:3541-3546. 2009
- Are Cancer-Related Decision Aids Effective? A Systematic Review and Meta-Analysis. Journal of Clinical Oncology. 27:974-985. 2009
- Neurodevelopmental Outcome of Extremely Low Birth Weight Infants Randomly Assigned to Restrictive or Liberal Hemoglobin Thresholds for Blood Transfusion. Pediatrics. 123:207-213. 2009
- Using a Count of Neonatal Morbidities to Predict Poor Outcome in Extremely Low Birth Weight Infants: Added Role of Neonatal Infection. Pediatrics. 123:313-318. 2009
- Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study. Lancet Neurology. 7:875-884. 2008
- Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke. New England Journal of Medicine. 359:1238-1251. 2008
- Telmisartan to Prevent Recurrent Stroke and Cardiovascular Events. New England Journal of Medicine. 359:1225-1237. 2008
- Prevention and 18-Month Outcomes of Serious Pulmonary Hemorrhage in Extremely Low Birth Weight Infants: Results From the Trial of Indomethacin Prophylaxis in Preterms. Pediatrics. 121:e233-e238. 2008
- Evidence-Based Neonatal Drug Therapy for Prevention of Bronchopulmonary Dysplasia in Very-Low-Birth-Weight Infants. Neonatology. 93:284-287. 2008
- Long-Term Effects of Caffeine Therapy for Apnea of Prematurity. New England Journal of Medicine. 357:1893-1902. 2007
- Role of the implantable defibrillator among elderly patients with a history of life-threatening ventricular arrhythmias. European Heart Journal. 28:1746-1749. 2007
- Response to the Letter to the Editor by Dr Wijeysundera. American Heart Journal. 153:e19-e19. 2007
- Neurosensory Impairment after Surgical Closure of Patent Ductus Arteriosus in Extremely Low Birth Weight Infants: Results from the Trial of Indomethacin Prophylaxis in Preterms. Journal of Pediatrics. 150:229-234.e1. 2007
- The effects of perioperative β-blockade: Results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial. American Heart Journal. 152:983-990. 2006
- Antiarrhythmic Therapy for Prevention of Implantable Cardioverter Defibrillator Shocks—Reply. Journal of the American Medical Association (JAMA). 296:1229-1229. 2006
- In reply [3]. Journal of the American Medical Association (JAMA). 296:1230. 2006
- The premature infants in need of transfusion (pint) study: A randomized, controlled trial of a restrictive (LOW) versus liberal (HIGH) transfusion threshold for extremely low birth weight infants. Journal of Pediatrics. 149:301-307.e3. 2006
- Caffeine for apnea of prematurity - Reply. New England Journal of Medicine. 355:959-960. 2006
- The authors reply [10]. New England Journal of Medicine. 355:959-960. 2006
- Effect of Amiodarone and Sotalol on Ventricular Defibrillation Threshold. Circulation. 114:104-109. 2006
- Cardiovascular Outcomes With Atrial-Based Pacing Compared With Ventricular Pacing. Circulation. 114:11-17. 2006
- Indomethacin prophylaxis, patent ductus arteriosus, and the risk of bronchopulmonary dysplasia: Further analyses from the Trial of Indomethacin Prophylaxis in Preterms (TIPP). Journal of Pediatrics. 148:730-734.e1. 2006
- Caffeine Therapy for Apnea of Prematurity. New England Journal of Medicine. 354:2112-2121. 2006
- Retrospective economic evaluation of a controlled trial of indomethacin prophylaxis for patent ductus arteriosus in premature infants. Early Human Development. 82:97-103. 2006
- Comparison of β-Blockers, Amiodarone Plus β-Blockers, or Sotalol for Prevention of Shocks From Implantable Cardioverter Defibrillators<SUBTITLE>The OPTIC Study: A Randomized Trial</SUBTITLE>. Journal of the American Medical Association (JAMA). 295:165-165. 2006
- How Many Patients? How Many Limbs? Analysis of Patients or Limbs in the Orthopaedic Literature: A Systematic Review. Journal of Bone and Joint Surgery. American volume. 88:41-41. 2006
- Male/Female Differences in Indomethacin Effects in Preterm Infants. Journal of Pediatrics. 147:860-862. 2005
- Reply. Journal of Pediatrics. 147:717-717. 2005
- Thermal management of the extremely low birth weight infants at birth. Journal of Pediatrics. 147:716-717. 2005
- Heparin-Induced Skin Lesions and Other Unusual Sequelae of the Heparin-Induced Thrombocytopenia Syndrome. Chest. 127:1857-1861. 2005
- Cost-effectiveness of physiologic pacing: Results of the Canadian Health Economic Assessment of Physiologic Pacing. Heart Rhythm. 2:270-275. 2005
- Prophylactic Use of an Implantable Cardioverter–Defibrillator after Acute Myocardial Infarction. New England Journal of Medicine. 351:2481-2488. 2004
- Early Closure of the Watterberg Trial. Pediatrics. 114:1670-1671. 2004
- Heat Loss Prevention (HeLP) in the delivery room: A randomized controlled trial of polyethylene occlusive skin wrapping in very preterm infants. Journal of Pediatrics. 145:750-753. 2004
- Positive end-expiratory pressure above lower inflection point minimizes influx of activated neutrophils into lung*. Critical Care Medicine. 32:2471-2475. 2004
- Can extra protamine eliminate heparin rebound following cardiopulmonary bypass surgery?. Journal of Thoracic and Cardiovascular Surgery. 128:211-219. 2004
- Metoprolol prophylaxis against postoperative atrial fibrillation increases length of hospital stay in patients not on pre-operative blockers: the blocker length of stay (BLOS) trial. Heart. 90:941-942. 2004
- Diminishing proportional risk of sudden death with advancing age: implications for prevention of sudden death. American Heart Journal. 147:837-840. 2004
- Canadian Trial of Physiological Pacing. Circulation. 109:357-362. 2004
- ##Title##. Pediatric Research. 56:503. 2004
- An Improved Definition of Immune Heparin-Induced Thrombocytopenia in Postoperative Orthopedic Patients. JAMA Internal Medicine. 163:2518-2518. 2003
- Ethical Aspects in Trials of Implantable Medical Devices. Journal of the American Medical Association (JAMA). 290:1579-1579. 2003
- Ethical Aspects in Trials of Implantable Medical Devices—Reply. Journal of the American Medical Association (JAMA). 290:1579-1579. 2003
- Pacemaker Therapy for Prevention of Syncope in Patients With Recurrent Severe Vasovagal Syncope. Journal of the American Medical Association (JAMA). 289:2224-2224. 2003
- Impact of Bronchopulmonary Dysplasia, Brain Injury, and Severe Retinopathy on the Outcome of Extremely Low-Birth-Weight Infants at 18 Months. Journal of the American Medical Association (JAMA). 289:1124-1124. 2003
- Long-term amiodarone therapy and the risk of complications after cardiac surgery: Results from the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial (CAMIAT). Journal of Thoracic and Cardiovascular Surgery. 125:633-637. 2003
- Double-blind, placebo-controlled, randomized trial of prophylactic metoprolol for reduction of hospital length of stay after heart surgery: The β-Blocker Length Of Stay (BLOS) study. American Heart Journal. 145:226-232. 2003
- Ibuprofen prophylaxis in preterm neonates. The Lancet. 360:492-492. 2002
- Quality of life in the Canadian Implantable Defibrillator Study (CIDS). American Heart Journal. 144:282-289. 2002
- Effects of exercise training in patients with heart failure: The Exercise Rehabilitation Trial (EXERT). American Heart Journal. 144:23-30. 2002
- A randomized controlled trial comparing the frequency of acute reactions to plasma‐removed platelets and prestorage WBC‐reduced platelets. Transfusion. 42:556-566. 2002
- Evaluating “old” definitions for the “new” bronchopulmonary dysplasia. Journal of Pediatrics. 140:555-560. 2002
- The relationships of left ventricular ejection fraction, end-systolic volume index and infarct size to six-month mortality after hospital discharge following myocardial infarction treated by thrombolysis. Journal of the American College of Cardiology. 39:30-36. 2002
- Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke. Neurology. 57:1603-1610. 2001
- Effect of Clinical Risk Stratification on Cost-Effectiveness of the Implantable Cardioverter-Defibrillator. Circulation. 104:1622-1626. 2001
- Progression to chronic atrial fibrillation after pacing: the Canadian Trial of Physiologic Pacing. Journal of the American College of Cardiology. 38:167-172. 2001
- Long-Term Effects of Indomethacin Prophylaxis in Extremely-Low-Birth-Weight Infants. New England Journal of Medicine. 344:1966-1972. 2001
- Relationship Between Pacemaker Dependency and the Effect of Pacing Mode on Cardiovascular Outcomes. Circulation. 103:3081-3085. 2001
- Cost-Effectiveness of the Implantable Cardioverter-Defibrillator. Circulation. 103:1416-1421. 2001
- Fibrinolytic Variables in Patients with Recurrent Venous Thrombosis: a Prospective Cohort Study. Thrombosis and Haemostasis. 85:390-394. 2001
- Meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. European Heart Journal. 21:2071-2078. 2000
- Comparison of post transfusion platelet response following random donor and apheresis platelets. Blood. 96. 2000
- Impact of fluconazole prophylaxis on fungal colonization and infection rates in neutropenic patients. Journal of Antimicrobial Chemotherapy. 46:1001-1008. 2000
- Impact of fluconazole prophylaxis on fungal colonization and infection rates in neutropenic patients. The Canadian Fluconazole Study.. Journal of Antimicrobial Chemotherapy. 46:1001-1008. 2000
- Treatment of Proximal Deep Vein Thrombosis With a Novel Synthetic Compound (SR90107A/ORG31540) With Pure Anti–Factor Xa Activity. Circulation. 102:2726-2731. 2000
- The Defibrillator in Acute Myocardial Infarction Trial (DINAMIT): Study protocol. American Heart Journal. 140:735-739. 2000
- The impact of time to thrombolytic treatment on outcome in patients with acute myocardial infarction. Heart. 84:142-148. 2000
- Effects of Physiologic Pacing versus Ventricular Pacing on the Risk of Stroke and Death Due to Cardiovascular Causes. New England Journal of Medicine. 342:1385-1391. 2000
- Intra-arterial Prourokinase for Acute Ischemic Stroke. Journal of the American Medical Association (JAMA). 283:2102-2104. 2000
- Identification of Patients Most Likely to Benefit From Implantable Cardioverter-Defibrillator Therapy. Circulation. 101:1660-1664. 2000
- Canadian Implantable Defibrillator Study (CIDS). Circulation. 101:1297-1302. 2000
- The Stroke Prognosis Instrument II (SPI-II). Stroke. 31:456-462. 2000
- Depression and Risk of Sudden Cardiac Death After Acute Myocardial Infarction: Testing for the Confounding Effects of Fatigue. Psychosomatic Medicine. 61:729-737. 1999
- A peacemaker reduced the recurrence of syncope in patients with severe vasovagal syncope. Evidence-Based Medicine. 4:154. 1999
- Monthly intra-individual variation in lipids over a 1-year period in 22 normal subjects. Clinical Biochemistry. 32:381-389. 1999
- A randomized controlled trial comparing plasma removal with white cell reduction to prevent reactions to platelets. Transfusion. 39:231-238. 1999
- Do sick newborn infants benefit from participation in a randomized clinical trial?. Journal of Pediatrics. 134:151-155. 1999
- Poor adherence to placebo or amiodarone therapy predicts mortality: results from the CAMIAT study. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial.. Psychosomatic Medicine. 61:566-575. 1999
- The North American vasovagal pacemaker study (VPS). Journal of the American College of Cardiology. 33:16-20. 1999
- Heparin Improves Gas Exchange during Experimental Acute Lung Injury in Newborn Piglets. American Journal of Respiratory and Critical Care Medicine. 158:1620-1625. 1998
- A Placebo-controlled Randomized Trial of Antithrombin Therapy in Neonatal Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine. 158:470-476. 1998
- Evolving Indications for Permanent Pacing in Patients with Vasovagal Syncope. Journal of Interventional Cardiac Electrophysiology. 2:52-53. 1998
- Erratum: Amiodarone reduced ventricular fibrillation or arrhythmic death in MI with frequent ventricular premature depolarizations (Evidence-Based Medicine (September-October 1997) 2:142)). Evidence-Based Medicine. 2:167. 1997
- Amiodarone after myocardial infarction: EMIAT and CAMIAT trials.. The Lancet. 349:1767. 1997
- North American Vasovagal Pacemaker Study: Study Design and Organization. PACE - Pacing and Clinical Electrophysiology. 20:844-848. 1997
- Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. The Lancet. 349:675-682. 1997
- CAPRIE trial. The Lancet. 349:356-356. 1997
- CAPRIE trial.. The Lancet. 349:354-355. 1997
- Comparison of mortality from acute myocardial infarction between 1979 and 1992 in a geographically defined stable population. American Journal of Cardiology. 78:1345-1349. 1996
- Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group.. Journal of the National Cancer Institute. 88:1659-1664. 1996
- A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). The Lancet. 348:1329-1339. 1996
- Fish Oils and Low-Molecular-Weight Heparin for the Reduction of Restenosis After Percutaneous Transluminal Coronary Angioplasty. Circulation. 94:1553-1560. 1996
- Myocardial Ischemia Detected by Ambulatory Monitoring after Myocardial Infarction. New England Journal of Medicine. 334:1545-1546. 1996
- Canadian atrial fibrillation anticoagulation study: were the patients subsequently treated with warfarin? Canadian Atrial Fibrillation Anticoagulation Study Group.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 154:1669-1674. 1996
- Prognostic Importance of Myocardial Ischemia Detected by Ambulatory Monitoring Early after Acute Myocardial Infarction. New England Journal of Medicine. 334:65-71. 1996
- Precision and Accuracy of Clinical and Radiological Signs in Premature Infants at Risk of Patent Ductus Arteriosus. JAMA Pediatrics. 149:1136-1136. 1995
- Does it matter how coronary projections are combined to assess restenosis following PTCA?. International Journal of Cardiovascular Imaging. 11:145-149. 1995
- The Incidence of First Hickman Catheter-Related Infection and Predictors of Catheter Removal in Cancer Patients. Infection Control and Hospital Epidemiology. 16:451-458. 1995
- Heparin-Induced Thrombocytopenia in Patients Treated with Low-Molecular-Weight Heparin or Unfractionated Heparin. New England Journal of Medicine. 332:1330-1336. 1995
- Ability to distinguish whisky (uisge beatha) from brandy (cognac). The BMJ. 309:1686-1688. 1994
- Reports of Independent Analyses of Data From the Worldwide Prospective Collaborative Study on Immunotherapy for Unexplained Recurrent Spontaneous Abortion. Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy. 32:275-278. 1994
- Graded exercise testing following thrombolytic therapy for acute myocardial infarction: the importance of timing and infarct location. TPAT Study Group.. Canadian Journal of Cardiology. 10:897-904. 1994
- Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: results from a randomized trial. Investigators of the Ontario Clinical Oncology Group.. International Journal of Radiation Oncology Biology Physics. 30:11-16. 1994
- Early treatment of stroke with monosialoganglioside GM-1. Efficacy and safety results of the Early Stroke Trial.. Stroke. 25:1552-1558. 1994
- Cancer of the respiratory tract in nickel sinter plant workers: effect of removal from sinter plant exposure.. Occupational and Environmental Medicine. 51:19-22. 1994
- Canadian Amiodarone Myocardial Infarction Arrhythmia Trial (CAMIAT): Rationale and protocol. American Journal of Cardiology. 72:F87-F94. 1993
- Canadian Implantable Defibrillator Study (CIDS): Study design and organization. American Journal of Cardiology. 72:F103-F108. 1993
- A prospective study to identify the risk factors associated with acute reactions to platelet and red cell transfusions. Transfusion. 33:794-797. 1993
- Prevalence of small opacities in chest radiographs of nickel sinter plant workers.. Occupational and Environmental Medicine. 50:428-431. 1993
- Pooled outcome measures in arthritis: the pros and cons.. Journal of Rheumatology. 20:566-567. 1993
- Amiodarone for patients with ventricular premature depolarizations after myocardial infarction. Is it safe to stop treatment at one year?. Circulation. 87:637-639. 1993
- Focal Cerebral Ischemia in Young Adults: A Collaborative Case-Control Study. Neuroepidemiology. 12:70-81. 1993
- Hypertrophic Sternal Scars. Plastic and Reconstructive Surgery. 90:988-992. 1992
- Failure of Aspirin plus Dipyridamole To Prevent Restenosis after Carotid Endarterectomy. ACP journal club. 116:731-736. 1992
- POLYCYCLIC AROMATIC HYDROCARBONS (PAHs): A POSSIBLE CAUSE OF LUNG CANCER MORTALITY AMONG NICKEL/COPPER SMELTER AND REFINERY WORKERS. AIHA journal : a journal for the science of occupational and environmental health and safety. 53:317-324. 1992
- Polyclinic Aromatic Hydrocarbons (PAHs): A Possible Cause of Lung Cancer Mortality among Nickel/Copper Smelter and Refinery Workers. AIHA journal : a journal for the science of occupational and environmental health and safety. 53:317-324. 1992
- Design and baseline results of the monosialoganglioside early stroke trial. The EST Study Group.. Stroke. 23:519-526. 1992
- Thrombin/Antithrombin III Complex Formation in the Neonatal Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine. 145:767-770. 1992
- How Should Results from Completed Studies Influence Ongoing Clinical Trials?. ACP journal club. 115:818-822. 1991
- Canadian atrial fibrillation anticoaguiation (CAFA) study. Journal of the American College of Cardiology. 18:349-355. 1991
- Post-myocardial infarction mortality in patients with ventricular premature depolarizations. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Pilot Study.. Circulation. 84:550-557. 1991
- Coronary patency, infarct size and left ventricular function after thrombolytic therapy for acute myocardial infarction: results from the tissue plasminogen activator: Toronto (TPAT) placebo-controlled trial. Journal of the American College of Cardiology. 17:1451-1457. 1991
- Cyclophosphamide and plasma exchange in multiple sclerosis. The Lancet. 337:1540-1541. 1991
- Effect of Pregnancy on Airway Responsiveness and Asthma Severity: Relationship to Serum Progesterone. American Review of Respiratory Disease. 143:S78-S78. 1991
- A standard heparin nomogram for the management of heparin therapy. JAMA Internal Medicine. 151:333-337. 1991
- Prolonged hemorrhagic shock does not impair regeneration of plasma coagulant masses in the rabbit. Critical Care Medicine. 19:253-259. 1991
- When is a prognostic factor useful? A guide for the perplexed.. Journal of Clinical Oncology. 9:348-356. 1991
- Reliability of a Standardized Mini-Mental State Examination compared with the traditional Mini-Mental State Examination. American Journal of Psychiatry. 148:102-105. 1991
- A Classic Manuscript Reprinted in Celebration of 25 Years of Progress. Journal of the American Association of Nurse Practitioners. 2:93-99. 1990
- A randomized trial comparing 12 weeks versus 36 weeks of adjuvant chemotherapy in stage II breast cancer.. Journal of Clinical Oncology. 8:1217-1225. 1990
- Low-dose cyclosporin versus placebo in patients with rheumatoid arthritis. The Lancet. 335:1051-1055. 1990
- N of 1 randomized trials for investigating new drugs. Contemporary Clinical Trials. 11:88-100. 1990
- Problem Resolution and Repetition of Parasuicide. The British journal of psychiatry. Supplement. 156:395-399. 1990
- Why Parasuicides Repeat Despite Problem Resolution. The British journal of psychiatry. Supplement. 156:399-405. 1990
- Therapeutic priorities of Canadian internists.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 142:329-333. 1990
- Assessment of observer variation in measuring the radiographic vertebral index in patients with multiple myeloma. Journal of Clinical Epidemiology. 43:833-840. 1990
- Improvement in Airway Responsiveness and Asthma Severity during Pregnancy: A Prospective Study. American Journal of Respiratory and Critical Care Medicine. 140:924-931. 1989
- THE CANADIAN AMERICAN TICLOPIDINE STUDY (CATS) IN THROMBOEMBOLIC STROKE. The Lancet. 333:1215-1220. 1989
- Tissue plasminogen activator: Toronto (TPAT) placebo-controlled randomized trial in acute myocardial infarction. Journal of the American College of Cardiology. 13:1469-1476. 1989
- Canadian and American study of ticlopidine in thromboembolic cerebrovascular accidents. Revista Brasileira de Neurologia. 25:171-172. 1989
- The Canadian American Ticlopidine Study (CATS) in thromboembolic stroke. Design, organization, and baseline results.. Stroke. 19:1203-1210. 1988
- A clinician's guide for conducting randomized trials in individual patients.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 139:497-503. 1988
- An Assessment of Clinically Useful Measures of the Consequences of Treatment. New England Journal of Medicine. 318:1728-1733. 1988
- Concentration response relationships of amiodarone and desethylamiodarone. American Heart Journal. 115:1208-1213. 1988
- The role of evidence in the consensus process. Results from a Canadian consensus exercise. Journal of the American Medical Association (JAMA). 259:3001-3005. 1988
- Methylmercury and the health of autochthons in northwest Quebec.. Clinical and Investigative Medicine. 11:71-98. 1988
- An N of 1 Service: Applying the Scientific Method in Clinical Practice. Scandinavian Journal of Gastroenterology, Supplement. 23:22-29. 1988
- A Cautionary Tale About Investigations of the Effect of the Menstrual Cycle on Asthma: Reply. American Journal of Respiratory and Critical Care Medicine. 136:1515-1516. 1987
- Clinical Significance of a Test for Slime Production in Ventriculoperitoneal Shunt Infections Caused by Coagulase-Negative Staphylococci. Journal of Infectious Diseases. 156:555-560. 1987
- A Controlled Trial of Teaching Critical Appraisal of the Clinical Literature to Medical Students. Journal of the American Medical Association (JAMA). 257:2451-2451. 1987
- Airway responsiveness to methacholine during the natural menstrual cycle and the effect of oral contraceptives.. American Journal of Respiratory and Critical Care Medicine. 135:1039-1042. 1987
- Bench-to-bedside research and the human tumor stem-cell assay--bridging the credibility gap.. Journal of Clinical Oncology. 4:1730-1731. 1986
- Polyethylene glycol-modified ragweed extract: Comparison of two treatment regimens. Journal of Allergy and Clinical Immunology. 78:851-856. 1986
- Airway responses to hyperventilation of cold dry air: Duration of protection by cromolyn sodium. Journal of Allergy and Clinical Immunology. 78:387-391. 1986
- Workshop 4: The role of bronchoprovocation. Journal of Allergy and Clinical Immunology. 78:517-524. 1986
- A Meta-analysis of the Studies of Dihydroergotamine plus Heparin in the Prophylaxis of Deep Vein Thrombosis. Chest. 89:396S-400S. 1986
- Determining Optimal Therapy — Randomized Trials in Individual Patients. New England Journal of Medicine. 314:889-892. 1986
- A Study of Mortality in Workers Engaged in the Mining, Smelting, and Refining of Nickel: I: Methodology and Mortality by Major Cause Groups. Toxicology and Industrial Health. 5:957-974. 1985
- A Study of Mortality in Workers Engaged in the Mining, Smelting, and Refining of Nickel: Ii: Mortality from Cancer of the Respiratory Tract and Kidney. Toxicology and Industrial Health. 5:975-993. 1985
- Psychosocial adjustment of burn survivors. Burns. 12:28-35. 1985
- The effect of inhaled hexamethonium bromide and atropine sulphate on airway responsiveness to histamine. Journal of Allergy and Clinical Immunology. 76:97-103. 1985
- Differences in responsiveness to hyperventilation and methacholine in asthma and chronic bronchitis.. Thorax. 40:422-426. 1985
- A secondary prevention, randomized trial of suloctidil in patients with a recent history of thromboembolic stroke.. Stroke. 16:416-424. 1985
- Asymptomatic bronchial hyperresponsiveness in rhinitis. Journal of Allergy and Clinical Immunology. 75:573-577. 1985
- Polyethylene glycol-modified ragweed pollen extract in rhinoconjunctivitis. Journal of Allergy and Clinical Immunology. 75:578-585. 1985
- Effect of beclomethasone dipropionate on bronchial responsiveness to histamine in controlled nonsteroid-dependent asthma. Journal of Allergy and Clinical Immunology. 75:25-30. 1985
- A Mortality Study of 11,500 Nickel Workers<xref ref-type="fn" rid="FN2">2</xref>. Journal of the National Cancer Institute. 73:1251-1258. 1984
- Bronchial responsiveness to methacholine in chronic bronchitis: relationship to airflow obstruction and cold air responsiveness.. Thorax. 39:912-918. 1984
- Is cimetidine being prescribed indiscriminately? An analytic survey of patients who present with symptoms of peptic ulcer disease.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 131:443-447. 1984
- The effect of atropine on allergen-induced increases in bronchial responsiveness to histamine.. American Journal of Respiratory and Critical Care Medicine. 130:368-372. 1984
- Lung epithelial permeability: relation to nonspecific airway responsiveness. Journal of applied physiology. 57:77-84. 1984
- Prediction of late asthmatic responses to inhaled allergen. Clinical and Experimental Allergy. 14:379-385. 1984
- A mortality study of Falconbridge workers.. IARC (International Agency for Research on Cancer) Scientific Publications. 117-124. 1984
- Cancer mortality associated with the high-temperature oxidation of nickel subsulfide.. IARC (International Agency for Research on Cancer) Scientific Publications. 23-35. 1984
- When is a patient's use of primary care services unwarranted? Some answers from physicians.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 129:822-827. 1983
- The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction stimulated by airway cooling.. American Journal of Respiratory and Critical Care Medicine. 128:611-617. 1983
- Bronchoconstriction Stimulated by Airway Cooling. American Journal of Respiratory and Critical Care Medicine. 128:440-443. 1983
- Asthma and increases in nonallergic bronchial responsiveness from seasonal pollen exposure. Journal of Allergy and Clinical Immunology. 71:399-406. 1983
- Inhibition of the bronchial response to respiratory heat exchange by increasing doses of terbutaline sulphate.. Thorax. 37:913-917. 1982
- Some Physical Signs in Patients with Chronic Airflow Obstruction1,2. American Journal of Respiratory and Critical Care Medicine. 125:549-552. 1982
- [Not Available].. Canadian Family Physician. 28:840-842. 1982
- What is Unwarranted Use of a Doctor's Services?. Canadian Family Physician. 28:582-585. 1982
- WHAT IS UNJUSTIFIED USAGE OF THE PHYSICIANS SERVICES. Canadian Family Physician. 28:840-842. 1982
- Multiple choice questions for continuing education in family medicine.. Journal of Family Practice. 13:1031-1035. 1981
- High-altitude retinopathy. Journal of the American Medical Association (JAMA). 245:581-586. 1981
- Standardization of inhalation provocation tests: two techniques of aerosol generation and inhalation compared.. American Journal of Respiratory and Critical Care Medicine. 123:195-199. 1981
- The concept of disease. The BMJ. 2:757-762. 1979
- The effect of the province of Ontario's compulsory seatbelt legislation in an urban area.. Canadian Journal of Public Health. 70:28-33. 1979
- Reply. American Heart Journal. 96:422-423. 1978
- Selection of medical students at McMaster University.. Clinical Medicine. 12:365-378. 1978
- COMPLIANCE WITH ANTIHYPERTENSIVE DRUG THERAPY*. Annals of the New York Academy of Sciences. 304:390-403. 1978
- An empirical demonstration of Berkson's bias. Journal of Clinical Epidemiology. 31:119-128. 1978
- Patient compliance with antihypertensive regimens. Patient Counselling and Health Education. 1:18-21. 1978
- Studies on the pharmacokinetics and pharmacodynamics of atenolol in man. European Journal of Clinical Pharmacology. 13:81-89. 1978
- Hypertension control, compliance and science. American Heart Journal. 94:666-667. 1977
- Commentary. Clinical Pharmacology and Therapeutics. 22:125-130. 1977
- The epidemiology of traffic accidents and the effect of the 1969 breathalyser amendment in Canada. Accident Analysis and Prevention. 8:201-206. 1976
- Nurse practitioners in primary care. V. Development of the utilization and financial index to measure effects of their deployment.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 114:1099-1102. 1976
- Nurse practitioners in primary care. VI. Assessment of their deployment with the Utilization and Financial Index.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 114:1103-1108. 1976
- IMPROVEMENT OF MEDICATION COMPLIANCE IN UNCONTROLLED HYPERTENSION. The Lancet. 307:1265-1268. 1976
- Patterns of medical drug use - a community focus.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 114:33-37. 1976
- Inhibition of Injury Induced Thromboatherosclerotic Lesions by Anti-Platelet Serum in Rabbits. Thrombosis and Haemostasis. 35:070-081. 1976
- RANDOMISED CLINICAL TRIAL OF STRATEGIES FOR IMPROVING MEDICATION COMPLIANCE IN PRIMARY HYPERTENSION. The Lancet. 305:1205-1207. 1975
- Test-retest reliability of the wide range achievement test. Journal of Clinical Psychology. 31:81-84. 1975
- The Burlington Randomized Trial of the Nurse Practitioner: Health Outcomes of Patients. ACP journal club. 80:137-137. 1974
- The Burlington Randomized Trial of the Nurse Practitioner. New England Journal of Medicine. 290:251-256. 1974