Alexithymia in PTSD: psychometric and FMRI studies. Journal Articles

abstract

• Two studies examined correlates of alexithymia in posttraumatic stress disorder (PTSD). In study 1 (n = 77 individuals with PTSD and 45 controls) Toronto alexithymia scale (TAS-20) scores were positively correlated with PTSD symptoms, dissociation, and childhood abuse and neglect. In study 2, TAS-20 scores were examined as correlates of functional magnetic resonance imaging (fMRI) blood oxygen level dependent (BOLD) response to trauma script imagery. In 16 controls, TAS-20 scores correlated positively with response in medial prefrontal cortex (mPFC), and negatively with response in anterior cingulate cortex (ACC) and thalamus. In 26 individuals with PTSD, TAS-20 scores correlated positively with response in insula, posterior cingulate cortex (PCC), and thalamus, and negatively with response in ACC.

authors

• Frewen, Paul A
• Pain, Claire
• Dozois, David JA
• Lanius, Ruth

status

• published 

publication date

• July 2006

has subject area

• Adult (MeSH)
• Affective Symptoms (MeSH)
• Cerebral Cortex (MeSH)
• Child (MeSH)
• Child Abuse (MeSH)
• Dissociative Disorders (MeSH)
• Emotions (MeSH)
• General Science & Technology (Science Metrix)
• Humans (MeSH)
• Magnetic Resonance Imaging (MeSH)
• Oxygen (MeSH)
• Prefrontal Cortex (MeSH)
• Psychiatric Status Rating Scales (MeSH)
• Psychometrics (MeSH)
• Stress Disorders, Post-Traumatic (MeSH)
• Thalamus (MeSH)

published in

• Annals of the New York Academy of Sciences  Journal

keywords

• Adult
• Affective Symptoms
• Cerebral Cortex
• Child
• Child Abuse
• Dissociative Disorders
• Emotions
• Humans
• Magnetic Resonance Imaging
• Oxygen
• Prefrontal Cortex
• Psychiatric Status Rating Scales
• Psychometrics
• Stress Disorders, Post-Traumatic
• Thalamus

Digital Object Identifier (DOI)

• 10.1196/annals.1364.029

PubMed ID

• 16891585

start page

• 397

end page

• 400

volume

• 1071

issue

• 1