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Global Effect of Cardiovascular Risk Factors on...
Journal article

Global Effect of Cardiovascular Risk Factors on Lifetime Estimates

Abstract

BACKGROUND: Five risk factors account for approximately 50% of the global burden of cardiovascular disease. How the presence or absence of classic risk factors affects lifetime estimates of cardiovascular disease and death from any cause remains unclear. METHODS: We harmonized individual-level data from 2,078,948 participants across 133 cohorts, 39 countries, and 6 continents. Lifetime risk of cardiovascular disease and death from any cause was …

Authors

Magnussen C; Alegre-Diaz J; Al-Nasser LA; Amouyel P; Aviles-Santa L; Bakker SJL; Ballantyne CM; Bernabé-Ortiz A; Bobak M; Boffetta P

Journal

The New England Journal of Medicine, Vol. 393, No. 2, pp. 125–138

Publisher

Massachusetts Medical Society

Publication Date

July 10, 2025

DOI

10.1056/nejmoa2415879

ISSN

0028-4793