Venous thromboembolism prophylaxis in traumatic brain injury after radiographic progression: a 6-year experience at a single Canadian Level 1 trauma Centre

BACKGROUND: Patients with traumatic brain injury are at high risk for venous thromboembolism. Therefore, pharmacological prophylaxis for venous thromboembolism has become critical in managing trauma patients. Unfortunately, the decision to initiate prophylaxis in patients with radiographic progression must be carefully weighed against the risk of further progression of intracranial haemorrhage, with little evidence to support decision-making.