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Genotoxicity assessment of magnetic iron oxide...
Journal article

Genotoxicity assessment of magnetic iron oxide nanoparticles with different particle sizes and surface coatings

Abstract

Magnetic iron oxide nanoparticles (IONPs) have been widely used for various biomedical applications such as magnetic resonance imaging and drug delivery. However, their potential toxic effects, including genotoxicity, need to be thoroughly understood. In the present study, the genotoxicity of IONPs with different particle sizes (10, 30 nm) and surface coatings (PEG, PEI) were assessed using three standard genotoxicity assays, the Salmonella …

Authors

Liu Y; Xia Q; Liu Y; Zhang S; Cheng F; Zhong Z; Wang L; Li H; Xiao K

Journal

Nanotechnology, Vol. 25, No. 42,

Publisher

IOP Publishing

Publication Date

October 24, 2014

DOI

10.1088/0957-4484/25/42/425101

ISSN

0957-4484