Journal article
Some actions of chandonium iodide, a new short‐acting muscle relaxant, in anaesthetized cats and on isolated muscle preparations
Abstract
1. The actions of the new skeletal muscle relaxant chandonium (HS310) on the cardiovascular, respiratory and skeletal muscle systems of the cat under chloralose anaesthesia and on chick and rat isolated skeletal muscle preparations have been described. 2. In the cat chandonium exhibited a potent, competitive, non-depolarizing neuromuscular blocking action that was rapid in onset and of short duration. It possessed a selective atropine-like …
Authors
Gandiha A; Marshall IG; Paul D; Rodger IW; Scott W; Singh H
Journal
Clinical and Experimental Pharmacology and Physiology, Vol. 2, No. 2, pp. 159–170
Publisher
Wiley
Publication Date
April 1975
DOI
10.1111/j.1440-1681.1975.tb01830.x
ISSN
0305-1870
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AcetylcholineAndrostenesAnimalsAzasteroidsCatsChick EmbryoChickensCholinesterase InhibitorsDiaphragmElectric StimulationFemaleGanglionic BlockersHeart RateIn Vitro TechniquesMaleMusclesNeuromuscular Blocking AgentsNeuromuscular JunctionNictitating MembranePhrenic NervePyrrolidinesQuaternary Ammonium CompoundsRatsRespirationSciatic NerveVagus Nerve