Journal article
Increased Small Bowel Epithelial Turnover in Interleukin-1 Receptor Knockout Mice
Abstract
OBJECTIVE: To determine whether interleukin-1 (IL-1) affects the cellular homeostasis of small bowel mucosa, the authors studied apoptosis and proliferation in small bowel epithelium in two groups of C57 mice: an IL-1 receptor knockout group, and a control wild-type group.
SUMMARY BACKGROUND DATA: Gut mucosal integrity is maintained by a balance of cell proliferation and cell death. Recent reports suggest that IL-1, a proinflammatory cytokine, …
Authors
Wolf SE; Debroy MA; Ikeda H; Jeschke M; Matin S; Rajaraman S; Ko TC; Englander EW; Norman JG; Thompson JC
Journal
Annals of Surgery, Vol. 232, No. 1, pp. 42–45
Publisher
Wolters Kluwer
Publication Date
July 2000
DOI
10.1097/00000658-200007000-00006
ISSN
0003-4932