Journal article
Gene expression using microarrays in transplant recipients at risk of EBV lymphoproliferation after organ transplantation: Preliminary proof‐of‐concept
Abstract
We hypothesized that aspects of the virus-host interaction could be measured to help predict progression to EBV-PTLD. We examined the spectrum of host genes differentially expressed and any relevant clustering in children at risk of EBV lymphoproliferation after organ transplantation. We compared the genes expressed among patients with different levels of viral loads. Gene expression was measured by microarray analysis of RNA from CD19+ B …
Authors
Allen U; Barton M; Beyene J; Hu P; Khodai‐Booran N; Hébert D; Dipchand A; Ng V; Solomon M; Grant D
Journal
Pediatric Transplantation, Vol. 13, No. 8, pp. 990–998
Publisher
Wiley
Publication Date
12 2009
DOI
10.1111/j.1399-3046.2009.01193.x
ISSN
1397-3142
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentCase-Control StudiesChildChild, PreschoolEpstein-Barr Virus InfectionsFemaleGene Expression ProfilingHumansImmunosuppressive AgentsInfantLymphoproliferative DisordersMaleOligonucleotide Array Sequence AnalysisOrgan TransplantationPolymerase Chain ReactionPostoperative ComplicationsViral Load