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Sucralfate mouthwash for prevention and treatment...
Journal article

Sucralfate mouthwash for prevention and treatment of 5-fluorouracil-induced mucositis: a randomized, placebo-controlled trial

Abstract

Abstract. A randomized, double-blind, placebo-controlled trial was conducted to evaluate the effectiveness of a sucralfate mouthwash in preventing and alleviating oral mucositis induced by 5-fluorouracil (5FU). A total of 81 patients with colorectal cancer were enrolled. Patients were studied during their first cycle of chemotherapy with 5FU and leucovorin (LV) daily for 5 days every 4 weeks (Mayo Clinic schedule). Patients were randomly …

Authors

Nottage M; McLachlan S-A; Brittain M-A; Oza A; Hedley D; Feld R; Siu LL; Pond G; Moore MJ

Journal

Supportive Care in Cancer, Vol. 11, No. 1, pp. 41–47

Publisher

Springer Nature

Publication Date

1 2003

DOI

10.1007/s00520-002-0378-8

ISSN

0941-4355