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Absorbed photodynamic dose from pulsed versus...
Journal article

Absorbed photodynamic dose from pulsed versus continuous wave light examined with tissue-simulating dosimeters.

Abstract

A dosimetric system has been developed to measure the spatially resolved light dose absorbed by a photosensitizer in a tissue-simulating medium. These gelatin-based dosimeters had macroscopic optical scattering and absorption properties that are typical for homogeneous tissue and contained the photosensitizer benzoporphyrin derivative monoacid (BPD-MA). A reporter molecule, 2?7?-dichlorofluorescin diacetate (DCF-DA), served as an actinometer, …

Authors

Pogue BW; Lilge L; Patterson MS; Wilson BC; Hasan T

Journal

Applied Optics, Vol. 36, No. 28, pp. 7257–7269

Publisher

Optica Publishing Group

Publication Date

October 1, 1997

DOI

10.1364/ao.36.007257

ISSN

1559-128X