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Journal article

Comments on the opinions published by Bergman et al. (2015) on Critical Comments on the WHO-UNEP State of the Science of Endocrine Disrupting Chemicals (Lamb et al., 2014)

Abstract

Recently Bergman et al. (2015) took issue with our comments (Lamb et al., 2014) on the WHO-UNEP(1) report entitled the "State of the Science of Endocrine Disrupting Chemicals - 2012" (WHO 2013a). We find several key differences between their view and ours regarding the selection of studies and presentation of data related to endocrine disrupting chemicals (EDCs) under the WHO-IPCS(2) definition (2002). In this response we address the factors that we think are most important: 1. the difference between hazard and risk; 2. the different approaches for hazard identification (weight of the evidence [WOE] vs. emphasizing positive findings over null results); and 3. the lack of a justification for conceptual or practical differences between EDCs and other groups of agents.

Authors

Lamb JC; Boffetta P; Foster WG; Goodman JE; Hentz KL; Rhomberg LR; Staveley J; Swaen G; Van Der Kraak G; Williams AL

Journal

Regulatory Toxicology and Pharmacology, Vol. 73, No. 3, pp. 754–757

Publisher

Elsevier

Publication Date

December 1, 2015

DOI

10.1016/j.yrtph.2015.10.029

ISSN

0273-2300

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