Journal article
Identification of Penumbra and Infarct in Acute Ischemic Stroke Using Computed Tomography Perfusion–Derived Blood Flow and Blood Volume Measurements
Abstract
BACKGROUND AND PURPOSE: We investigated whether computed tomography (CT) perfusion-derived cerebral blood flow (CBF) and cerebral blood volume (CBV) could be used to differentiate between penumbra and infarcted gray matter in a limited, exploratory sample of acute stroke patients.
METHODS: Thirty patients underwent a noncontrast CT (NCCT), CT angiography (CTA), and CT perfusion (CTP) scan within 7 hours of stroke onset, NCCT and CTA at 24 …
Authors
Murphy BD; Fox AJ; Lee DH; Sahlas DJ; Black SE; Hogan MJ; Coutts SB; Demchuk AM; Goyal M; Aviv RI
Journal
Stroke, Vol. 37, No. 7, pp. 1771–1777
Publisher
Wolters Kluwer
Publication Date
7 2006
DOI
10.1161/01.str.0000227243.96808.53
ISSN
0039-2499
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Acute DiseaseAdultAgedAged, 80 and overBlood Flow VelocityBlood VolumeBrain IschemiaCell SurvivalCerebral AngiographyCerebrovascular CirculationFemaleHumansImage Processing, Computer-AssistedInfarction, Middle Cerebral ArteryMaleMiddle AgedPerfusionReperfusionSensitivity and SpecificityTomography, X-Ray Computed