Journal article
Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men
Abstract
Mitochondrial dysfunction may contribute to age-associated muscle atrophy. Previous data has shown that resistance exercise (RE) increases mitochondrial gene expression and enzyme activity in older adults; however, the acute response to RE has not been well characterized. To characterize the acute mitochondrial response to unaccustomed RE, healthy young (21 ± 3 yr) and older (70 ± 4 yr) men performed a unilateral RE bout for the knee extensors. …
Authors
Ogborn DI; McKay BR; Crane JD; Safdar A; Akhtar M; Parise G; Tarnopolsky MA
Journal
AJP Regulatory Integrative and Comparative Physiology, Vol. 308, No. 8, pp. r734–r741
Publisher
American Physiological Society
Publication Date
April 15, 2015
DOI
10.1152/ajpregu.00005.2014
ISSN
0363-6119