A robust platinum-based electrochemical micro flow cell for drying of [18F]fluoride for pet tracer synthesis

A platinum-based electrochemical micro flow cell has been designed to repeatedly extract [¹⁸F]fluoride from an aqueous solution in a fast and reliable fashion, and release the trapped ions into an anhydrous solvent. Compared with previous approaches, the use of noble metals for both the cathode and the anode in the cell allows application of higher potentials enabling faster trapping and release of F-18 ions and reducing contamination of the released solution.