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Genetic analysis of Caenorhabditis elegans...
Journal article

Genetic analysis of Caenorhabditis elegans pry-1/Axin suppressors identifies genes involved in reproductive structure development, stress responses, and aging

Abstract

The Axin family of scaffolding proteins regulates a wide array of developmental and post-developmental processes in eukaryotes. Studies in the nematode Caenorhabditis elegans have shown that the Axin homolog PRY-1 plays essential roles in multiple tissues. To understand the genetic network of pry-1, we focused on a set of genes that are differentially expressed in the pry-1-mutant transcriptome and are linked to reproductive structure …

Authors

Mallick A; Jhaveri N; Jeon J; Chang Y; Shah K; Hosein H; Gupta BP

Journal

G3: Genes, Genomes, Genetics, Vol. 12, No. 2,

Publisher

Oxford University Press (OUP)

Publication Date

February 4, 2022

DOI

10.1093/g3journal/jkab430

ISSN

2160-1836