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Effect of Lactate on the Recovery of Cho-Ki Cells...
Journal article

Effect of Lactate on the Recovery of Cho-Ki Cells from Gamma Radiation Damage

Abstract

The effect of pre-exposure of CHO-KI cells to lactate on their capacity to recover from or repair radiation damage was examined. Prolonged pre-exposure to lactate and a number of inhibitors of glycolysis has previously been shown to reduce the cell survival after irradiation. Following a split dose of irradiation, cells pre-treated with lactate for 18 hours had a higher relative recovery factor than controls even though survival following a …

Authors

Mothersill C; Seymour CB

Journal

Acta Oncologica, Vol. 25, No. 1, pp. 71–76

Publisher

Taylor & Francis

Publication Date

January 1986

DOI

10.3109/02841868609136381

ISSN

0284-186X