Journal article
Accelerated brain aging in major depressive disorder and antidepressant treatment response: A CAN-BIND report
Abstract
OBJECTIVES: Previous studies suggest that major depressive disorder (MDD) may be associated with volumetric indications of accelerated brain aging. This study investigated neuroanatomical signs of accelerated aging in MDD and evaluated whether a brain age gap is associated with antidepressant response.
METHODS: Individuals in a major depressive episode received escitalopram treatment (10-20 mg/d) for 8 weeks. Depression severity was assessed at …
Authors
Ballester PL; Suh JS; Nogovitsyn N; Hassel S; Strother SC; Arnott SR; Minuzzi L; Sassi RB; Lam RW; Milev R
Journal
NeuroImage Clinical, Vol. 32, ,
Publisher
Elsevier
Publication Date
2021
DOI
10.1016/j.nicl.2021.102864
ISSN
2213-1582