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Utility of a Cancer Predisposition Screening Tool...
Journal article

Utility of a Cancer Predisposition Screening Tool for Predicting Subsequent Malignant Neoplasms in Childhood Cancer Survivors

Abstract

PURPOSE: Childhood cancer survivors (CCS) are at risk of developing subsequent malignant neoplasms (SMNs) resulting from exposure to prior therapies. CCS with underlying cancer predisposition syndromes are at additional genetic risk of SMN development. The McGill Interactive Pediatric OncoGenetic Guidelines (MIPOGG) tool identifies children with cancer at increased likelihood of having a cancer predisposition syndrome, guiding clinicians …

Authors

Cullinan N; Schiller I; Di Giuseppe G; Mamun M; Reichman L; Cacciotti C; Wheaton L; Caswell K; Di Monte B; Gibson P

Journal

Journal of Clinical Oncology, Vol. 39, No. 29, pp. 3207–3216

Publisher

American Society of Clinical Oncology (ASCO)

Publication Date

October 10, 2021

DOI

10.1200/jco.21.00018

ISSN

0732-183X