Journal article
Molecular mechanisms of membrane targeting antibiotics
Abstract
The bacterial membrane provides a target for antimicrobial peptides. There are two groups of bacteria that have characteristically different surface membranes. One is the Gram-negative bacteria that have an outer membrane rich in lipopolysaccharide. Several antimicrobials have been found to inhibit the synthesis of this lipid, and it is expected that more will be developed. In addition, antimicrobial peptides can bind to the outer membrane of …
Authors
Epand RM; Walker C; Epand RF; Magarvey NA
Journal
Biochimica et Biophysica Acta, Vol. 1858, No. 5, pp. 980–987
Publisher
Elsevier
Publication Date
May 2016
DOI
10.1016/j.bbamem.2015.10.018
ISSN
0006-3002