Journal article
Health-Related Quality of Life and Fatigue in Children and Adults with Pyruvate Kinase Deficiency
Abstract
Pyruvate kinase deficiency (PKD) is the most common cause of congenital nonspherocytic hemolytic anemia. Although recognition of the disease spectrum has recently expanded, data describing its impact on health-related quality of life (HRQoL) are limited. In this prospective international cohort of 254 patients (131 adults and 123 children) with PKD, we used validated measures to assess the impact of disease on HRQoL (EuroQol 5-Dimension …
Authors
Al-Samkari H; van Beers EJ; Morton DH; Eber SW; Chonat S; Kuo KHM; Kollmar N; Wang H; Breakey VR; Sheth S
Journal
Blood Advances, Vol. 6, No. 6, pp. 1844–1853
Publisher
American Society of Hematology
Publication Date
March 22, 2022
DOI
10.1182/bloodadvances.2021004675
ISSN
2473-9529