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Excess of rare variants in genes identified by...
Journal article

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

Abstract

Robert Hegele and colleagues report a genome-wide association study for hypertriglyceridemia, followed by resequencing of the coding regions of candidate genes. They identify an excess of rare variants in affected individuals at four genes within the associated loci.

Authors

Johansen CT; Wang J; Lanktree MB; Cao H; McIntyre AD; Ban MR; Martins RA; Kennedy BA; Hassell RG; Visser ME

Journal

Nature Genetics, Vol. 42, No. 8, pp. 684–687

Publisher

Springer Nature

Publication Date

8 2010

DOI

10.1038/ng.628

ISSN

1061-4036