Proceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015

Table of contentsA1 Role of fibrocytes in allergic rhinitisMarie-Ève Côté, Marie-Ève Boulay, Sophie Plante, Jamila Chakir, Louis-Philippe BouletA2 Patterns of aeroallergens sensitization in Northern AlbertaHanan Ahmed, Maria-Beatriz Ospina, Kyriaki Sideri, Harissios VliagoftisA3 Addressing acceptable risk for adolescents with Food-Induced Anaphylaxis (FIA)Sara F. Johnson, Roberta L. WoodgateA4 Outcomes of matched related and unrelated bone marrow transplantation after reduced-toxicity conditioning for children suffering from Chronic Granulomatous DiseaseGuilhem Cros, Pierre Teira, Sonia Cellot, Henrique Bittencourt, Helene Decaluwe, Marie France Vachon, Michel Duval, Elie HaddadA5 Outcomes of patients with severe combined immunodeficiency (SCID) prior to and after initiation of newborn screening for SCID in OntarioVy H.D. Kim, Anne Pham-Huy, Eyal GrunebaumA6 Detection of regulatory B cells in the airways of subjects with asthmaJohn-Paul Oliveria, Stephanie Phan, Mark W. Tenn, Damian Tworek, Steven G. Smith, Adrian J. Baatjes, Caitlin D. Obminski, Caroline E. Munoz, Tara X. Scime, Roma Sehmi, Gail M GauvreauA7 Characterization of IgE-expressing B cells in the airways and peripheral blood of allergic asthmatic subjectsJohn-Paul Oliveria, Stephanie Phan, Mark W. Tenn, Brittany M Salter, Steven G Smith, Caitlin D Obminski, Caroline E Munoz, Abbey Schlatman, Tara X Scime, Rick Watson, Roma Sehmi, Gail M GauvreauA8 Pregnancy: could it be a risk factor for primary immunodeficient patientsRoya Sherkat, Razieh Khoshnevisan, Saba SheikhbahaeiA9 Clinical experience with Octagam: a Canadian retrospective chart reviewStephen Betschel, Richard Warrington, Robert SchellenbergA10 Kounis syndrome secondary to contrast media with inferior ST elevations and bilateral ischemic strokeMichael N Fein, Jean-Philippe PelletierA11 Honey bee venom immunotherapy ineffective in bumble bee-induced anaphylaxis: case report and review of literatureManstein Kan, Robert SchellenbergA12 Delayed immune reconstitution occurring after multiple immune complications of hematological stem cell transplantation for a leaky SCIDRoxane Labrosse, Guilhem Cros, Pierre Teira, Henrique Bittencourt, Helene Decaluwe, Michel Duval, Elie HaddadA13 Comparison of Three Case Reports of Acquired Angioedema: presentation, management and outcomeRaymond Mak, James Loh, Amin KananiA14 Sitagliptin-associated angioedema not related to concurrent use of ARB or ACE inhibitorDominik A. Nowak, Paul K. KeithA15 Sneddon-Wilkinson subcorneal pustular dermatosis associated with an IgA monoclonal gammopathyDaniel Pannozzo, Dominik A. Nowak, Hermenio C. LimaA16 Omalizumab can be effective in patients with allergic bronchopulmonary aspergillosisDiana Pham, Hoang Pham, Gonzalo G. Alvarez, Istvan T. Bencze, Krishna B. Sharma, Mark Smith, Shawn Aaron, Jennifer Block, Tara Keays, Judith Leech, David Schneidermen, Jodi Cameron, Jennifer Forgie, Alicia Ring, John W. O’Quinn, Stephanie Santucci, William H. YangA17 Efficacious use of omalizumab in the treatment of cystic fibrosisDiana Pham, Hoang Pham, Ena Gaudet, Shawn Aaron, Stephanie Santucci, William H. YangA18 HAE with normal C1-INH with inconsistent response to C1 esterase inhibitor infusion but reliably responsive to icatibantHoang Pham, Stephanie Santucci, William H. YangA19 Anaphylaxis reaction to lactase enzymeMathew R. Voisin, Rozita Borici-MaziA20 Risk of solid tumor malignancies in patients with primary immune deficiencyKateryna Vostretsova, Donald F. StarkA21 Is it time to adopt the chromogenic assay for measuring C1 esterase inhibitor function in patients with HAE Type 2?Elizabeth Yeboah, Paul K. KeithA22 Emergency department visits for anaphylaxis and allergic reactionsMichelle Martin-Rhee, Cheryl Gula, Clare Cheng, Geoff PaltserA23 START: Susceptibility To food Allergies in a Registry of TwinsAlizée Dery, Ann Clarke, Kari Nadeau, Laurie Harada, Kimberley Weatherall, Celia Greenwood, Denise Daley, Yuka Asai, Moshe Ben-ShoshanA24 Qualifying the diagnostic approach employed by allergists when managing patients with self-diagnosed non-celiac gluten sensitivity (NCGS)Lee Horgan, Teresa PunA25 Retrospective analysis on the agreement between skin prick test and serum food specific IgE antibody in adults with suspected food allergyLing Ling, Maria B. Ospina, Kyriaki Sideri, Harissios VliagoftisA26 Staple food hypersensitivity from infancy to adolescence: a report from the BAMSE cohortJennifer L.P. Protudjer, Mirja Vetander, Marianne van Hage, Ola Olén, Magnus Wickman, Anna BergströmA27 Evaluating the impact of supervised epinephrine autoinjector administration during food challenges on perceived parent confidenceTimothy Teoh, Christopher Mill, Tiffany Wong, Ingrid Baerg, Angela Alexander, Kyla J. Hildebrand, John Dean, Boris Kuzeljevic, Edmond S. ChanA28 Local immunoglobulin production to Aspergillus fumigatus cystic fibrosisJonathan Argeny, Mia Gona-Hoepler, Petra Fucik, Edith Nachbaur, Saskia Gruber, Reto Crameri, Andreas Glaser, Zsolt Szépfalusi, Claudio Rhyner, Thomas EiweggerA29 Extract consumption with skin prick test (SPT) devicesGreg. Plunkett, Brad MireA30 Evaluation of our cases with nonsteroidal anti-inflammatory drug reactionsMehtap Yazicioglu, Ceren Can, Gokce CiplakA31 Reasons for referral and final diagnoses in a tertiary care pediatric allergy clinicVictoria E. Cook, Kyla J. Hildebrand, Elodie Portales-Casamar, Christopher Mill, Edmond S. ChanA32 Internist referral practices for inpatients with self-reported penicillin allergies at a tertiary care teaching hospitalMichael N Fein, Emil P NashiA33 Assessing the risk of reactions in children with a negative oral challenge after a subsequent use of amoxicillinSofianne Gabrielli, Christopher Mill, Marie-Noel Primeau, Christine Lejtenyi, Elena Netchiporouk, Alizee Dery, Greg Shand, Moshe Ben-ShoshanA34 Validity of self-reported penicillin allergiesErica Hoe, Joel LiemA35 Effectiveness of allergy-test directed elimination diets in eosinophilic esophagitisJason K. Ko, David J.T. Huang, Jorge A. MazzaA36 Allergy testing and dietary management in pediatric eosinophilic esophagitis (EoE): A retrospective review of a tertiary Canadian centre’s experienceMary McHenry, Anthony Otley,Wade WatsonA37 Visualizing the impact of atopic and allergic skin diseaseDominik A. Nowak, John N. KraftA38 Cystic fibrosis with and without nasal polyposis in pediatric patients: a cross-sectional comparative studyMihaela Paina, Ahmed A. Darwish Hassan, Delia Heroux, Lynn Crawford, Gail Gauvreau, Judah Denburg, Linda Pedder, Paul K. KeithA39 Evaluation of macrolide antibiotic hypersensitivity: the role of oral challenges in childrenBahar Torabi, Marie-Noel Primeau, Christine Lejtenyi, Elaine Medoff, Jennifer Mill, Moshe Ben-ShoshanA40 Venom allergy testing: is a graded approach necessary?Jaclyn A. Quirt, Xia Wen, Jonathan Kim, Angel Jimenez Herrero, Harold L. KimA41 The role of oral challenges in evaluating cephalosporin hypersensitivity reactions in childrenMagdalena J. Grzyb, Marie-Noël Primeau, Christine Lejtenyi, Elaine Medoff, Jennifer Mill, Moshe Ben-ShoshanA42 Breastfeeding and infant wheeze, atopy and atopic dermatitis: findings from the Canadian Healthy Infant Longitudinal Development StudyMeghan B. Azad, Zihang Lu, Allan B. Becker, Padmaja Subbarao, Piushkumar J. Mandhane, Stuart E. Turvey, Malcolm R. Sears, the CHILD Study InvestigatorsA43 IL33 DNA methylation in bronchial epithelial cells is associated to asthmaAnne-Marie Boucher-Lafleur, Valérie Gagné-Ouellet, Éric Jacques, Sophie Plante, Jamila Chakir, Catherine LapriseA44 NRF2 mediates the antioxidant response to organic dust-induced oxidative stress in bronchial epithelial cellsMichael Chen, Toby McGovern, Mikael Adner, James G. MartinA45 The effects of perinatal distress, immune biomarkers and mother-infant interaction quality on childhood atopic dermatitis (rash) at 18 monthsNela Cosic, Henry Ntanda, Gerald Giesbrecht, Anita Kozyrskyj, Nicole LetourneauA46 Examining the immunological mechanisms associated with cow’s milk allergyBassel Dawod, Jean MarshallA47 Tryptase levels in children presenting with anaphylaxis to the Montréal Children’s HospitalSarah De Schryver, Michelle Halbrich, Ann Clarke, Sebastian La Vieille, Harley Eisman, Reza Alizadehfar, Lawrence Joseph, Judy Morris, Moshe Ben-ShoshanA48 Secondhand tobacco smoke exposure in infancy and the development of food hypersensitivity from childhood to adolescenceLaura Y. Feldman, Jesse D. Thacher, Inger Kull, Erik Melén, Göran Pershagen, Magnus Wickman, Jennifer L. P. Protudjer, Anna BergströmA49 Combined exposure to diesel exhaust and allergen enhances allergic inflammation in the bronchial submucosa of atopic subjectsAli Hosseini, Tillie L. Hackett, Jeremy Hirota, Kelly McNagny, Susan Wilson, Chris CarlstenA50 Comparison of skin-prick test measurements by an automated system against the manual methodSaiful Huq, Rishma Chooniedass, Brenda Gerwing, Henry Huang, Diana Lefebvre, Allan BeckerA51 The accurate identification and quantification of urinary biomarkers of asthma and COPD through the use of novel DIL- LC-MS/MS methodsMona M. Khamis, Hanan Awad, Kevin Allen, Darryl J. Adamko, Anas El-AneedA52 Systemic immune pathways associated with the mechanism of Cat-Synthetic Peptide Immuno-Regulatory Epitopes, a novel immunotherapy, in whole blood of cat-allergic peopleYoung Woong Kim, Daniel R. Gliddon, Casey P. Shannon, Amrit Singh, Pascal L. C. Hickey, Anne K. Ellis, Helen Neighbour, Mark Larche, Scott J. TebbuttA53 Reducing the health disparities: online support for children with asthma and allergies from low-income familiesErika Ladouceur, Miriam Stewart, Josh Evans, Jeff Masuda, Nicole Letourneau, Teresa To, Malcolm KingA54 Epigenetic association of PSORS1C1 and asthma in the Saguenay-Lac-Saint-Jean asthma studyMiriam Larouche, Liming Liang, Catherine LapriseA55 IL-33 induces cytokine and chemokine production in human mast cellsStephanie A. Legere, Ian D. Haidl, Jean-Francois Legaré, Jean S. MarshallA56 Reference ranges for lung clearance index from infancy to adolescence for Canadian populationZihang Lu, Malcolm Sears, Theo J. Moraes, Felix Ratjen, Per Gustafsson, Wendy Lou, Padmaja SubbaraoA57 Kingston Allergy Birth Cohort: cohort profile and mother/child characteristics to age 2Michelle L. North, Elizabeth Lee, Vanessa Omana, Jenny Thiele, Jeff Brook, Anne K. EllisA58 Cow’s milk protein specific IgE, IgA and IgG4 as a predictor of outcome in oral immunotherapyTanvir Rahman, Duncan Lejtenyi, Sarah De Schryver, Ryan Fiter, Ciriaco Piccirillo, Moshe Ben-Shoshan, Bruce MazerA59 Age of peanut introduction and development of reactions and sensitization to peanutElinor Simons, Allan B. Becker, Rishma Chooniedass, Kyla Hildebrand, Edmond S. Chan, Stuart Turvey, Padmaja Subbarao, Malcolm SearsA60 Multi-omic blood biomarker signatures of the late phase asthmatic responseAmrit Singh, Casey P. Shannon, Young Woong Kim, Mari DeMarco, Kim-Anh Le Cao, Gail M. Gauvreau, J. Mark FitzGerald, Louis-Philippe Boulet, Paul M. O’Byrne, Scott J. TebbuttA61 Early life gut microbial alterations in children diagnosed with asthma by three years of ageLeah T. Stiemsma, Marie-Claire Arrieta, Jasmine Cheng, Pedro A. Dimitriu, Lisa Thorson, Sophie Yurist, Boris Kuzeljevic, Diana L. Lefebvre, Padmaja Subbarao, Piush Mandhane, Allan Becker, Malcolm R. Sears, Kelly M. McNagny, Tobias Kollmann, the CHILD Study Investigators, William W. Mohn, B. Brett Finlay, Stuart E. TurveyA62 The relationship between food sensitization and atopic dermatitis at age 1 year in a Canadian birth cohortMaxwell M. Tran, Diana L. Lefebvre, Chinthanie F. Ramasundarahettige, Allan B. Becker, Wei Hao Dai, Padmaja Subbarao, Piush J. Mandhane, Stuart E. Turvey, Malcolm R. SearsA63 Allergen inhalation enhances Toll-like receptor-induced thymic stromal lymphopoietin receptor expression by hematopoietic progenitor cells in mild asthmaticsDamian Tworek, Delia Heroux, Seamus N. O’Byrne, Paul M. O’Byrne, Judah A. DenburgA64 The Allergic Rhinitis Clinical Investigator Collaborative – replicated eosinophilia on repeated cumulative allergen challenges in nasal lavage samplesLaura Walsh, Mena Soliman, Jenny Thiele, Lisa M. Steacy, Daniel E. Adams, Anne K. EllisA65 The CHILD Study: optimizing subject retention in pediatric longitudinal cohort researchLinda Warner, Mary Ann Mauro, Robby Mamonluk, Stuart E. TurveyA66 Differential expression of C3a and C5a in allergic asthmaChenXi Yang, Amrit Singh, Casey P. Shannon, Young Woong Kim, Ed M. Conway, Scott J. Tebbutt