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Structural covariance pattern abnormalities of...
Journal article

Structural covariance pattern abnormalities of insula in major depressive disorder: A CAN-BIND study report

Abstract

BACKGROUND AND METHODS: Investigation of the insula may inform understanding of the etiopathogenesis of major depressive disorder (MDD). In the present study, we introduced a novel gray matter volume (GMV) based structural covariance technique, and applied it to a multi-centre study of insular subregions of 157 patients with MDD and 93 healthy controls from the Canadian Biomarker Integration Network in Depression (CAN-BIND, …

Authors

Ge R; Hassel S; Arnott SR; Davis AD; Harris JK; Zamyadi M; Milev R; Frey BN; Strother SC; Müller DJ

Journal

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 111, ,

Publisher

Elsevier

Publication Date

December 2021

DOI

10.1016/j.pnpbp.2020.110194

ISSN

0278-5846