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Treatment of Proximal Deep Vein Thrombosis With a...
Journal article

Treatment of Proximal Deep Vein Thrombosis With a Novel Synthetic Compound (SR90107A/ORG31540) With Pure Anti–Factor Xa Activity

Abstract

BACKGROUND: Patients with venous thromboembolism require initial treatment with an immediate-acting anticoagulant, low-molecular-weight heparin. We evaluated a novel synthetic factor Xa inhibitor (SR90107a/ORG31540) as an alternative treatment. METHODS AND RESULTS: A randomized-parallel-group, phase II trial to assess the efficacy and safety of SR90107a/ORG31540 (5, 7.5, or 10 mg once daily) relative to low-molecular-weight heparin (dalteparin, …

Journal

Circulation, Vol. 102, No. 22, pp. 2726–2731

Publisher

Wolters Kluwer

Publication Date

November 28, 2000

DOI

10.1161/01.cir.102.22.2726

ISSN

0009-7322