Journal article
Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ONTARGET and TRANSCEND studies
Abstract
BACKGROUND: The role of atrial fibrillation in cognitive impairment and dementia, independent of stroke, is uncertain. We sought to determine the association of atrial fibrillation with cognitive and physical impairment in a large group of patients at high cardiovascular risk.
METHODS: We conducted a post-hoc analysis of two randomized controlled trials involving 31,546 patients, the aims of which were to evaluate the efficacy of treatment with …
Authors
Marzona I; O'Donnell M; Teo K; Gao P; Anderson C; Bosch J; Yusuf S
Journal
Canadian Medical Association Journal, Vol. 184, No. 6, pp. e329–e336
Publisher
Joule
Publication Date
April 3, 2012
DOI
10.1503/cmaj.111173
ISSN
0820-3946